SCHEMBL16644378

SCHEMBL16644378

C[Si](C)(C)C[C@H](CO)[C@@H](O)C[C@@H](O)CO

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.33
ALDH1A1 P00352 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7037092 0.78 LMNA (0.47) LMNAALDH1A1
SCHEMBL6543885 0.73
SCHEMBL2441992 0.73
SCHEMBL7150167 0.66 LMNA (0.44) LMNAALDH1A1
SCHEMBL7151383 0.66 LMNA (0.44) LMNAALDH1A1
SCHEMBL3223716 0.66 LMNA (0.44) LMNAALDH1A1
SCHEMBL4868129 0.66 LMNA (0.44) LMNAALDH1A1
SCHEMBL5919483 0.66 LMNA (0.44) LMNAALDH1A1
SCHEMBL7151040 0.66 LMNA (0.44) LMNAALDH1A1
SCHEMBL7595607 0.66 LMNA (0.44) LMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015051900-A1 PROCESS FOR THE PREPARATION OF ENTECAVIR THROUGH NOVEL INTERMEDIATES PHARMATHEN S.A. (GR) 2015-04-16 WO disclosed