SCHEMBL6543885

SCHEMBL6543885

C[Si](C)(C)C[C@@H](O)CO

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2441992 1.00
SCHEMBL6266103 0.83
SCHEMBL28919471 0.75
SCHEMBL4331475 0.73 LMNA (0.53)
SCHEMBL15068332 0.71 LMNA (0.36)
Glycerin SCHEMBL27697354 0.68
Glycerin SCHEMBL3262492 0.68 LMNA (0.82)
Glycerin SCHEMBL28212896 0.68 LMNA (0.82)
Glycerin SCHEMBL757035 0.68
Glycerin SCHEMBL549000 0.68 LMNA (0.82)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1175379-B1 METHOD FOR THE ASYMMETRIC DIHYDROXYLATION OF OLEFINS, USING OSMIUM CATALYSTS BAYER CHEMICALS AG (DE) 2004-01-02 EP disclosed
US-6472570-B1 Method for the asymmetric dihydroxylation of olefins, using osmium catalysts BAYER AKTIENGESELLSCHAFT (DE) 2002-10-29 US disclosed
EP-1175379-A1 METHOD FOR THE ASYMMETRIC DIHYDROXYLATION OF OLEFINS, USING OSMIUM CATALYSTS Bayer Aktiengesellschaft (DE) 2002-01-30 EP disclosed
WO-2000064844-A1 METHOD FOR THE ASYMMETRIC DIHYDROXYLATION OF OLEFINS, USING OSMIUM CATALYSTS BAYER AKTIENGESELLSCHAFT (DE) 2000-11-02 WO disclosed