Sugi Predict

Sugi Predict / Compounds / SCHEMBL1664457

SCHEMBL1664457

SCHEMBL1664457

C=Cn1cccc1C(=O)O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ POLB P06746 1/20 0.42
▸ APEX1 P27695 1/20 0.42
▸ TDP1 Q9NUW8 1/20 0.42
▸ L3MBTL1 Q9Y468 1/20 0.42
▸ HDAC4 P56524 1/20 0.38
▸ HDAC1 Q13547 1/20 0.38
▸ HDAC7 Q8WUI4 1/20 0.38
▸ HDAC8 Q9BY41 1/20 0.38
▸ HDAC6 Q9UBN7 1/20 0.38
▸ HDAC9 Q9UKV0 1/20 0.38
▸ HDAC5 Q9UQL6 1/20 0.38
▸ LMNA P02545 2/20 0.37
▸ MAPT P10636 2/20 0.37
▸ ALDH1A1 P00352 2/20 0.37
▸ MEN1 O00255 1/20 0.37
▸ ALOX12 P18054 1/20 0.37
▸ RECQL P46063 1/20 0.37
▸ KMT2A Q03164 1/20 0.37
▸ AKT1 P31749 1/20 0.34
▸ DAO P14920 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28211522 0.85 MEN1 (0.38) POLBAPEX1TDP1L3MBTL1LMNA
SCHEMBL27503049 0.82 ALDH1A1 (0.40) POLBAPEX1TDP1L3MBTL1LMNA
SCHEMBL4230925 0.81 TDP1 (0.43) POLBAPEX1TDP1L3MBTL1HDAC4
SCHEMBL4891297 0.79 POLB (0.42) POLBAPEX1TDP1L3MBTL1HDAC4
SCHEMBL29191015 0.76 POLB (0.40) POLBAPEX1TDP1L3MBTL1HDAC4
SCHEMBL11741711 0.73 HDAC1 (0.42) POLBAPEX1TDP1L3MBTL1HDAC4
SCHEMBL11625650 0.73 HDAC1 (0.42) POLBAPEX1TDP1L3MBTL1HDAC4
SCHEMBL11625643 0.73 HDAC1 (0.42) POLBAPEX1TDP1L3MBTL1HDAC4
SCHEMBL28878976 0.71 — —
SCHEMBL4739140 0.71 KMT2A (0.45) POLBAPEX1TDP1L3MBTL1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118663082-A Multilayer composite bionic structure oxygenation membrane and preparation method and application thereof 天津大学 2024-09-20 — — CN claimed
CN-117186136-A New preparation method of tris (dimethylamino) cyclopentadienyl zirconium 浙江博瑞电子科技有限公司 2023-12-08 — — CN claimed
US-9422502-B2 Low viscosity, low volatility lubricating oil basestocks EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2016-08-23 — — US claimed
WO-2015153022-A1 LOW VISCOSITY, LOW VOLATILITY LUBRICATING OIL BASESTOCKS EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2015-10-08 — — WO claimed
US-20150275128-A1 LOW VISCOSITY, LOW VOLATILITY LUBRICATING OIL BASESTOCKS EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2015-10-01 — — US claimed
CN-118663082-B Multilayer composite bionic structure oxygenation membrane and preparation method and application thereof 天津大学 2025-03-07 — — CN disclosed
CN-118663082-A Multilayer composite bionic structure oxygenation membrane and preparation method and application thereof 天津大学 2024-09-20 — — CN disclosed
EP-4396280-A1 DYNAMICALLY CROSSLINKABLE POLYMERIC COMPOSITIONS, ARTICLES, AND METHODS THEREOF Braskem S.A. (BR) 2024-07-10 — — EP disclosed
CN-117940503-A Dynamically crosslinkable polymer compositions, articles, and methods of making the same 布拉斯科有限公司 2024-04-26 — — CN disclosed
CN-117897072-A Dynamically crosslinkable polymer compositions, articles, and methods of making the same 布拉斯科有限公司 2024-04-16 — — CN disclosed
CN-117186136-A New preparation method of tris (dimethylamino) cyclopentadienyl zirconium 浙江博瑞电子科技有限公司 2023-12-08 — — CN disclosed
WO-2023031675-A1 DYNAMICALLY CROSSLINKABLE POLYMERIC COMPOSITIONS, ARTICLES, AND METHODS THEREOF BRASKEM S.A. (BR) 2023-03-09 — — WO disclosed
US-20140113990-A1 WATER BASED ANIONIC POLYMERS FOR INKJET INKS PENN COLOR, INC. (US) 2014-04-24 — — US disclosed
EP-2642994-A2 USE OF HEMATOPOIETIC GROWTH FACTOR MIMETICS Ligand Pharmaceuticals Incorporated (US) 2013-10-02 — — EP disclosed
CN-103282034-A Use of hematopoietic growth factor mimetics LIGAND PHARM INC 2013-09-04 — — CN disclosed
US-20120295904-A1 HEMATOPOIETIC GROWTH FACTOR MIMETIC SMALL MOLECULE COMPOUNDS AND THEIR USES LIGAND PHARMACEUTICALS INC. (US) 2012-11-22 — — US disclosed
CN-102656141-A Hematopoietic growth factor mimetic small molecule compounds and their uses LIGAND PHARM INC 2012-09-05 — — CN disclosed
EP-2488486-A1 HEMATOPOIETIC GROWTH FACTOR MIMETIC SMALL MOLECULE COMPOUNDS AND THEIR USES Ligand Pharmaceuticals Inc. (US) 2012-08-22 — — EP disclosed
WO-2012068406-A2 USE OF HEMATOPOIETIC GROWTH FACTOR MIMETICS LIGAND PHARMACEUTICALS INCORPORATED (US) 2012-05-24 — — WO disclosed
WO-2011046954-A1 HEMATOPOIETIC GROWTH FACTOR MIMETIC SMALL MOLECULE COMPOUNDS AND THEIR USES LIGAND PHARMACEUTICALS INC. (US) 2011-04-21 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120295904-A1 HEMATOPOIETIC GROWTH FACTOR MIMETIC SMALL MOLECULE COMPOUNDS AND THEIR USES MPL, CSF3R, HGF POLB 3224/4885APEX1 4614/4885TDP1 4089/4885
US-20150275128-A1 LOW VISCOSITY, LOW VOLATILITY LUBRICATING OIL BASESTOCKS F12, OR10J3, ATXN10 POLB 1230/4885APEX1 2851/4885TDP1 780/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.