Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.30 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11661758 | 0.80 | PPARA (0.60) | PPARANPSR1MCL1TSHR | |
| SCHEMBL15469204 | 0.77 | CYP1A2 (0.37) | NPSR1 | |
| SCHEMBL9849248 | 0.77 | PPARA (0.54) | PPARANPSR1MCL1TSHR | |
| SCHEMBL27348673 | 0.75 | PPARA (0.52) | PPARANPSR1MCL1TSHR | |
| SCHEMBL25623832 | 0.75 | EPHX2 (0.35) | PPARA | |
| SCHEMBL9548278 | 0.75 | PPARA (0.52) | PPARANPSR1MCL1TSHR | |
| SCHEMBL9849445 | 0.74 | PPARA (0.51) | PPARANPSR1TSHR | |
| Ammonia Solution, Strong SCHEMBL9548251 | 0.73 | PPARA (0.50) | PPARANPSR1TSHR | |
| SCHEMBL9849579 | 0.72 | PPARA (0.52) | PPARANPSR1TSHR | |
| SCHEMBL9548297 | 0.72 | PPARA (0.52) | PPARANPSR1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3336103-B1 | ANTIBODIES COMPRISING MULTIPLE SITE-SPECIFIC NON-NATURAL AMINO ACID RESIDUES, METHODS OF THEIR PREPARATION AND METHODS OF THEIR USE | SUTRO BIOPHARMA INC (US) | 2021-03-17 | — | — | EP | disclosed |
| EP-3055298-B1 | MODIFIED AMINO ACIDS COMPRISING TETRAZINE FUNCTIONAL GROUPS, METHODS OF PREPARATION, AND METHODS OF THEIR USE | SUTRO BIOPHARMA INC (US) | 2020-04-29 | — | — | EP | disclosed |
| EP-3336103-A1 | ANTIBODIES COMPRISING MULTIPLE SITE-SPECIFIC NON-NATURAL AMINO ACID RESIDUES, METHODS OF THEIR PREPARATION AND METHODS OF THEIR USE | Sutro Biopharma, Inc. (US) | 2018-06-20 | — | — | EP | disclosed |
| WO-2015054658-A1 | MODIFIED AMINO ACIDS COMPRISING TETRAZINE FUNCTIONAL GROUPS, METHODS OF PREPARATION, AND METHODS OF THEIR USE | SUTRO BIOPHARMA, INC. (US) | 2015-04-16 | — | — | WO | disclosed |