Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | PPARA | Q07869 | 3/20 | 0.45 |
| ▸ | CNR2 | P34972 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | THRA | P10827 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16632772 | 0.76 | FOLH1 (0.51) | MAPTALDH1A1KDM4EPTPN1MEN1 | |
| SCHEMBL11735828 | 0.76 | PTGS1 (0.50) | MAPTPPARAALDH1A1KDM4EMEN1 | |
| SCHEMBL17831977 | 0.76 | ALDH1A1 (0.51) | MAPTPPARACNR2ALDH1A1MEN1 | |
| SCHEMBL16645304 | 0.75 | CNR2 (0.43) | MAPTCNR2ALDH1A1KDM4ETHRA | |
| SCHEMBL15613417 | 0.73 | S1PR3 (0.62) | CNR2ALDH1A1KDM4ETHRATHRB | |
| SCHEMBL11928959 | 0.73 | TP53 (0.47) | CNR2THRATHRBPTPN11PTPN1 | |
| SCHEMBL9700149 | 0.72 | PLA2G2A (0.59) | PTPN11PTPN1PTPN6S1PR3TP53 | |
| SCHEMBL30374450 | 0.71 | TNKS (0.58) | MAPTPPARAALDH1A1MEN1KMT2A | |
| SCHEMBL10627084 | 0.71 | TNKS (0.58) | MAPTPPARAALDH1A1MEN1KMT2A | |
| SCHEMBL29102206 | 0.71 | CNR2 (0.65) | MAPTPPARACNR2ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150105337-A1 | ENTEROBACTIN CONJUGATES AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2015-04-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150105337-A1 | ENTEROBACTIN CONJUGATES AND USES THEREOF | BTD, VIP, SLC10A2 | MAPT 3311/4885PPARA 4489/4885CNR2 4047/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.