SCHEMBL1664547

SCHEMBL1664547

CCCCOc1ccccc1-c1nc(N(C)OCCCC)nc(N(OCCCC)OCCCC)n1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.46
CYP2C9 P11712 2/20 0.46
CYP2C19 P33261 2/20 0.46
CYP19A1 P11511 1/20 0.46
PDE5A O76074 6/20 0.41
PDE4A P27815 3/20 0.41
PDE4B Q07343 3/20 0.41
PDE4C Q08493 3/20 0.41
PDE4D Q08499 3/20 0.41
PTGDR2 Q9Y5Y4 1/20 0.36
HTR7 P34969 2/20 0.36
MCHR1 Q99705 1/20 0.36
TLR8 Q9NR97 1/20 0.36
GCGR P47871 1/20 0.35
HTR1B P28222 1/20 0.35
CSNK1A1 P48729 1/20 0.35
CSNK1D P48730 1/20 0.35
PRKCD Q05655 1/20 0.35
PAK1 Q13153 1/20 0.35
CAMK2B Q13554 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11421183 0.81 LMNA (0.31) SMN1; SMN2
SCHEMBL2746732 0.81 NPSR1 (0.42) PDE5AKDM4ETSHRSMN1; SMN2
SCHEMBL28928070 0.79 CYP1A2 (0.62) CYP1A2CYP2C9CYP2C19CYP19A1PDE5A
SCHEMBL29365709 0.79 CYP1A2 (0.62) CYP1A2CYP2C9CYP2C19CYP19A1PDE5A
SCHEMBL17292882 0.79 CYP1A2 (0.62) CYP1A2CYP2C9CYP2C19CYP19A1PDE5A
SCHEMBL9566557 0.73 CYP1A2 (0.56) CYP1A2CYP2C9CYP2C19CYP19A1PDE5A
SCHEMBL633501 0.72 ADRB2 (0.35) CYP1A2CYP2C9CYP2C19CYP19A1TSHR
SCHEMBL30497724 0.72 CYP1A2 (0.57) CYP1A2CYP2C9CYP2C19CYP19A1PDE5A
SCHEMBL28131881 0.71 PDE5A (0.52) CYP1A2CYP2C9CYP2C19CYP19A1PDE5A
SCHEMBL9355060 0.70 NPSR1 (0.40) PDE5AKDM4ETSHRSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4370583-A1 WATERBORNE COATING COMPOSITIONS BASED ON ACRYLIC GRAFTED UNSATURATED POLYESTERS CONTAINING DMPOA Eastman Chemical Company (US) 2024-05-22 EP disclosed
EP-4370619-A2 COATING COMPOSITIONS BASED ON UNSATURATED POLYESTER AND PHENOLIC RESIN Eastman Chemical Company (US) 2024-05-22 EP disclosed
EP-4370620-A2 UNSATURATED POLYESTER COMPOSITIONS FOR METAL PACKAGING COATINGS Eastman Chemical Company (US) 2024-05-22 EP disclosed
EP-4370432-A2 WATERBORNE COATING COMPOSITIONS BASED ON POLYESTERS CONTAINING DIMETHYLOL PROPIONIC ACID (DMPOA) Eastman Chemical Company (US) 2024-05-22 EP disclosed
EP-4370584-A1 WATERBORNE COATING COMPOSITIONS BASED ON ACRYLIC GRAFTED TMA-MODIFIED UNSATURATED POLYESTERS Eastman Chemical Company (US) 2024-05-22 EP disclosed
US-20240034905-A1 POLYESTER COMPOSITIONS FOR METAL PACKAGING COATINGS EASTMAN CHEMICAL COMPANY (US) 2024-02-01 US disclosed
US-20230400770-A1 Resist Underlayer Film Material, Patterning Process, And Method For Forming Resist Underlayer Film SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-12-14 US disclosed
EP-4290309-A1 RESIST UNDERLAYER FILM MATERIAL, PATTERNING PROCESS, AND METHOD FOR FORMING RESIST UNDERLAYER FILM SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-12-13 EP disclosed
US-20230374341-A1 COATING COMPOSITION CONTAINING TMCD POLYESTER AND A MODIFYING POLYESTER EASTMAN CHEMICAL COMPANY (US) 2023-11-23 US disclosed
EP-4236743-A1 POLYESTER COMPOSITIONS FOR METAL PACKAGING COATINGS Eastman Chemical Company (US) 2023-09-06 EP disclosed
EP-0382548-B1 Thermoplastic resin composition SUMITOMO CHEMICAL CO (JP) 1994-06-29 EP disclosed
US-5212256-A Impact strength SUMITOMO CHEMICAL CO., LTD. (JP) 1993-05-18 US disclosed
US-5206290-A Blend of polyphenylene ether, polyester and amino resin; molding materials; workability; impact strength; heat resistance; oil and gasoline resistance SUMITOMO CHEMICAL COMPANY (JP) 1993-04-27 US disclosed
US-5116906-A Molding materials SUMITOMO CHEMICAL CO., LTD. (JP) 1992-05-26 US disclosed
US-5112914-A Blend of polyphenylene ether, thermoplastic polyester and amino resin SUMITOMO CHEMICAL CO., LTD. (JP) 1992-05-12 US disclosed
US-4957967-A AMINO RESIN AND POLYESTER BLEND; HEAT RESISTANCE, IMPACT STRENGTH, MELT PROCESSABILITY SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1990-09-18 US disclosed
EP-0382548-A2 Thermoplastic resin composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1990-08-16 EP disclosed
EP-0381391-A2 Resin composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1990-08-08 EP disclosed
EP-0343876-A1 Thermoplastic resin composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1989-11-29 EP disclosed
US-4151220-A POLYESTER, AMINO RESIN, BLOCKED POLYISOCYANATE MARUZEN OIL CO., LTD. (JP) 1979-04-24 US disclosed