Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | ESR1 | P03372 | 3/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10493728 | 0.85 | ALDH1A1 (0.60) | KMT2ALMNASLC6A2ALDH1A1 | |
| SCHEMBL7429091 | 0.85 | ALDH1A1 (0.60) | KMT2ALMNASLC6A2ALDH1A1 | |
| SCHEMBL22279482 | 0.84 | RXRA (0.53) | MEN1KMT2AALDH1A1 | |
| SCHEMBL27635293 | 0.82 | MEN1 (0.55) | MEN1KMT2AESR1ESR2LMNA | |
| SCHEMBL18671827 | 0.81 | MEN1 (0.50) | MEN1KMT2AESR1ESR2LMNA | |
| SCHEMBL2742150 | 0.79 | MEN1 (0.52) | MEN1KMT2AESR1ESR2LMNA | |
| SCHEMBL15762727 | 0.77 | ALDH1A1 (0.48) | MEN1KMT2ALMNASLC6A2ALDH1A1 | |
| SCHEMBL126492 | 0.75 | ALDH1A1 (0.69) | MEN1KMT2AESR1ESR2LMNA | |
| SCHEMBL13590480 | 0.74 | TOP2A (0.54) | MEN1KMT2AESR1ESR2 | |
| SCHEMBL8268036 | 0.74 | LMNA (0.54) | MEN1KMT2AESR1ESR2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015052155-A1 | PROTECTING GROUP COMPRISING A PURIFICATION TAG | ASCENDIS PHARMA A/S (DK) | 2015-04-16 | — | — | WO | disclosed |