SCHEMBL16648672

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL16648688	0.84	LCAT (0.47)	MAP4K4HTR3EHTR3BHTR3AHTR3D
	SCHEMBL16664265	0.83	LCAT (0.48)	MAP4K4HTR3EHTR3BHTR3AHTR3D
	SCHEMBL16648809	0.82	PIM1 (0.44)	MAP4K4LCATDRD4DRD2DRD3
	SCHEMBL16648775	0.82	LCAT (0.49)	LCATPAK4PAK1DRD4DRD2
	SCHEMBL16648541	0.80	AVPR1A (0.47)	LCAT
	SCHEMBL16648907	0.79	HRH3 (0.50)	HTR3EHTR3BHTR3AHTR3DHTR3C
	SCHEMBL16648829	0.79	GPR119 (0.44)	MAP4K4LCATDRD4DRD2DRD3
	SCHEMBL16648618	0.78	LCAT (0.48)	MAP4K4LCATPAK4PAK1DRD4
	SCHEMBL16648414	0.78	LCAT (0.46)	LCATPAK4PAK1KCNH2DRD4
	SCHEMBL16648641	0.76	MAPT (0.46)	HTR3EHTR3BHTR3AHTR3DHTR3C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.