SCHEMBL16648809

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL16648672	0.82	MAP4K4 (0.49)	PIM1PIM3PIM2LCATDRD2
	SCHEMBL16648829	0.79	GPR119 (0.44)	LCATDRD2DRD4DRD3MAP4K4
	SCHEMBL16648414	0.75	LCAT (0.46)	LCATDRD2DRD4DRD3HTT
	SCHEMBL16648762	0.75	LCAT (0.46)	LCATDRD2DRD4DRD3
	SCHEMBL16648536	0.73	CHRNB2 (0.51)	LCATLMNAHTTSMN1; SMN2
	SCHEMBL16648647	0.73	LCAT (0.49)	LCATSMN1; SMN2NPSR1
	SCHEMBL16648618	0.73	LCAT (0.48)	LCATDRD2DRD4DRD3MAP4K4
	SCHEMBL16648527	0.72	LCAT (0.44)	PIM1LCATMAP4K4S1PR2LMNA
	SCHEMBL16648795	0.72	LCAT (0.45)	LCATDRD2DRD4DRD3S1PR2
	SCHEMBL16648748	0.72	LCAT (0.45)	LCATDRD2DRD4DRD3HRH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.