Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDR1 | Q08345 | 2/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.32 |
| ▸ | APLNR | P35414 | 1/20 | 0.32 |
| ▸ | SLC27A1 | Q6PCB7 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16870847 | 0.90 | DDR1 (0.39) | DDR1PDE10ABACE1CNR2MEN1 | |
| SCHEMBL16867099 | 0.84 | DDR1 (0.36) | DDR1PDE10AALDH1A1BACE1MEN1 | |
| SCHEMBL16867086 | 0.83 | NPC1 (0.37) | PDE10AALDH1A1MEN1CYP1A2CYP3A4 | |
| SCHEMBL17504821 | 0.81 | ALDH1A1 (0.37) | DDR1ALDH1A1APLNRHIF1A | |
| SCHEMBL16648948 | 0.78 | DDR1 (0.47) | DDR1ALDH1A1MEN1CYP1A2CYP3A4 | |
| SCHEMBL21484056 | 0.77 | NOTUM (0.37) | PDE10AALDH1A1BACE1MEN1CYP1A2 | |
| SCHEMBL16870923 | 0.72 | DDR1 (0.41) | DDR1PDE10A | |
| SCHEMBL29624418 | 0.71 | KEAP1 (0.46) | ALDH1A1MEN1CYP1A2CYP3A4KMT2A | |
| SCHEMBL20526107 | 0.71 | KEAP1 (0.46) | ALDH1A1MEN1CYP1A2CYP3A4KMT2A | |
| SCHEMBL20526096 | 0.71 | ABCG2 (0.40) | GPR55 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9271500-B2 | Fused heterocyclic compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2016-03-01 | — | — | US | disclosed |
| US-9271500-B2 | Fused heterocyclic compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2016-03-01 | — | — | US | disclosed |
| US-20150181880-A1 | FUSED HETEROCYCLIC COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2015-07-02 | — | — | US | disclosed |
| US-20150181880-A1 | FUSED HETEROCYCLIC COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2015-07-02 | — | — | US | disclosed |
| EP-2862853-A1 | FUSED HETEROCYCLIC COMPOUND | Sumitomo Chemical Co., Ltd (JP) | 2015-04-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150181880-A1 | FUSED HETEROCYCLIC COMPOUND | C5, CYC1, CYP1A1 | DDR1 4244/4885PDE10A 2906/4885ALDH1A1 1621/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.