Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.46 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.46 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.46 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | TEK | Q02763 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20526107 | 1.00 | KEAP1 (0.46) | KEAP1NFE2L2GPR55TLR8CA12 | |
| SCHEMBL20526096 | 0.91 | ABCG2 (0.40) | KEAP1NFE2L2GPR55TLR8CA12 | |
| SCHEMBL28232045 | 0.81 | CA1 (0.53) | KEAP1NFE2L2GPR55TLR8CA12 | |
| SCHEMBL20249061 | 0.78 | PTGS2 (0.42) | CA12CA1CA2CA9MEN1 | |
| SCHEMBL20526158 | 0.78 | NPC1 (0.43) | MEN1KMT2AKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL29624443 | 0.78 | NPC1 (0.43) | MEN1KMT2AKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL18328169 | 0.74 | ABCG2 (0.42) | CA12CA1CA2CA9CYP1A2 | |
| SCHEMBL20434182 | 0.73 | KCNH2 (0.48) | KEAP1NFE2L2KDRAURKAAURKB | |
| SCHEMBL23013853 | 0.72 | KDM1A (0.44) | TLR8MEN1KMT2AKDM4EHSD17B10 | |
| SCHEMBL16648786 | 0.71 | DDR1 (0.39) | GPR55MEN1KMT2AALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108368064-B | 1,2, 3-triazole derivative and insecticide and acaricide comprising the same as active ingredient | 北兴化学工业株式会社 | 2022-04-26 | — | — | CN | disclosed |