Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TBK1 | Q9UHD2 | 3/20 | 0.40 |
| ▸ | JAK2 | O60674 | 3/20 | 0.40 |
| ▸ | EGFR | P00533 | 3/20 | 0.39 |
| ▸ | ABL1 | P00519 | 4/20 | 0.38 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | PDE7A | Q13946 | 2/20 | 0.38 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.38 |
| ▸ | CSF1R | P07333 | 1/20 | 0.38 |
| ▸ | KIT | P10721 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1664139 | 0.98 | ALDH1A1 (0.44) | ALDH1A1MEN1KMT2ANPSR1RXFP1 | |
| SCHEMBL1664141 | 0.95 | KMT2A (0.48) | ALDH1A1MEN1KMT2ANPSR1RXFP1 | |
| SCHEMBL1664935 | 0.95 | KMT2A (0.48) | ALDH1A1MEN1KMT2ANPSR1RXFP1 | |
| SCHEMBL1664150 | 0.90 | SMN1; SMN2 (0.41) | ALDH1A1MEN1KMT2ANPSR1RXFP1 | |
| SCHEMBL1665596 | 0.88 | MAPT (0.54) | ALDH1A1MEN1KMT2ANPSR1RXFP1 | |
| SCHEMBL1664163 | 0.86 | SMN1; SMN2 (0.44) | ALDH1A1MEN1KMT2ANPSR1RXFP1 | |
| SCHEMBL1666904 | 0.86 | NPC1 (0.47) | ALDH1A1MEN1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL1664151 | 0.86 | KMT2A (0.46) | ALDH1A1MEN1KMT2ANPSR1RXFP1 | |
| SCHEMBL1663842 | 0.86 | MAOA (0.43) | ALDH1A1MEN1KMT2ANPSR1RXFP1 | |
| SCHEMBL1666906 | 0.84 | RAB9A (0.50) | ALDH1A1MEN1KMT2ASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2488486-A1 | HEMATOPOIETIC GROWTH FACTOR MIMETIC SMALL MOLECULE COMPOUNDS AND THEIR USES | Ligand Pharmaceuticals Inc. (US) | 2012-08-22 | — | — | EP | disclosed |
| WO-2011046954-A1 | HEMATOPOIETIC GROWTH FACTOR MIMETIC SMALL MOLECULE COMPOUNDS AND THEIR USES | LIGAND PHARMACEUTICALS INC. (US) | 2011-04-21 | — | — | WO | disclosed |