Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 11/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | PDE2A | O00408 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 2/20 | 0.34 |
| ▸ | PPARD | Q03181 | 2/20 | 0.34 |
| ▸ | PPARA | Q07869 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3182714 | 0.78 | KIF11 (0.51) | KIF11KDM1A | |
| SCHEMBL15156942 | 0.74 | MEN1 (0.42) | — | |
| SCHEMBL2821410 | 0.74 | MEN1 (0.42) | — | |
| SCHEMBL15157445 | 0.73 | KIF11 (0.50) | KIF11FFAR1KDM1A | |
| SCHEMBL585210 | 0.72 | KDM4E (0.50) | KIF11AKR1C3AKR1C2PPARGPPARD | |
| SCHEMBL585211 | 0.72 | KDM4E (0.50) | KIF11AKR1C3AKR1C2PPARGPPARD | |
| SCHEMBL15156611 | 0.71 | TRPV4 (0.39) | EPHX2 | |
| SCHEMBL16649842 | 0.70 | ALDH1A1 (0.46) | — | |
| SCHEMBL16649181 | 0.70 | ALDH1A1 (0.46) | — | |
| SCHEMBL16649856 | 0.70 | ALDH1A1 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2681215-B1 | SERINE/THREONINE KINASE INHIBITORS | ARRAY BIOPHARMA INC (US) | 2015-04-22 | — | — | EP | claimed |