Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 9/20 | 0.47 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | PPARD | Q03181 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | PDE2A | O00408 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15157445 | 0.81 | KIF11 (0.50) | KIF11KDM1AFFAR1APP | |
| SCHEMBL12498864 | 0.79 | KCNA3 (0.37) | PPARGPPARA | |
| SCHEMBL28196304 | 0.77 | KIF11 (0.49) | KIF11KDM1ACYP11B1CYP11B2 | |
| SCHEMBL16649704 | 0.77 | KIF11 (0.47) | KIF11KDM1AAPP | |
| SCHEMBL16649936 | 0.77 | KIF11 (0.47) | KIF11KDM1AAPP | |
| SCHEMBL3182714 | 0.77 | KIF11 (0.51) | KIF11KDM1A | |
| SCHEMBL16649545 | 0.77 | TRPA1 (0.39) | — | |
| SCHEMBL27642819 | 0.73 | KIF11 (0.54) | KIF11KDM1ACYP11B1CYP11B2 | |
| SCHEMBL29438427 | 0.72 | KIF11 (0.73) | KIF11KDM1ACYP11B1CYP11B2 | |
| SCHEMBL48409 | 0.72 | KIF11 (0.73) | KIF11KDM1ACYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2681215-B1 | SERINE/THREONINE KINASE INHIBITORS | ARRAY BIOPHARMA INC (US) | 2015-04-22 | — | — | EP | claimed |