Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | KRAS | P01116 | 4/20 | 0.38 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.38 |
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | DHODH | Q02127 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1665021 | 0.97 | ALDH1A1 (0.41) | TNIKALDH1A1KDM4EHPGDLMNA | |
| SCHEMBL1665971 | 0.88 | JAK2 (0.41) | TNIKALDH1A1HPGDNPSR1RXFP1 | |
| SCHEMBL1664054 | 0.87 | TNIK (0.42) | TNIKALDH1A1KDM4ELMNAEPHX2 | |
| SCHEMBL1666783 | 0.86 | SMYD3 (0.46) | TNIKSMYD3DHODHMAPTSYK | |
| SCHEMBL1666784 | 0.86 | SMYD3 (0.46) | TNIKKDM4ELMNASMYD3EPHX2 | |
| SCHEMBL8775930 | 0.85 | PIN1 (0.42) | TNIKALDH1A1LMNAEPHX2DHODH | |
| SCHEMBL1665973 | 0.84 | MEN1 (0.40) | TNIKALDH1A1HPGDNPSR1RXFP1 | |
| SCHEMBL1666719 | 0.83 | MAPT (0.39) | TNIKALDH1A1KDM4EHPGDLMNA | |
| SCHEMBL1664050 | 0.83 | DHODH (0.42) | TNIKALDH1A1LMNAEPHX2DHODH | |
| SCHEMBL1664697 | 0.82 | MAPT (0.41) | TNIKALDH1A1KDM4EHPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2488486-A1 | HEMATOPOIETIC GROWTH FACTOR MIMETIC SMALL MOLECULE COMPOUNDS AND THEIR USES | Ligand Pharmaceuticals Inc. (US) | 2012-08-22 | — | — | EP | disclosed |
| WO-2011046954-A1 | HEMATOPOIETIC GROWTH FACTOR MIMETIC SMALL MOLECULE COMPOUNDS AND THEIR USES | LIGAND PHARMACEUTICALS INC. (US) | 2011-04-21 | — | — | WO | disclosed |