Known targets — ChEMBL curated mechanism
GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHMGCRMMP1MMP13MMP7MMP8PTGS1PTGS2ileSpolrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Phosphonic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphonic Acid SCHEMBL385111 | 1.00 | — | — | |
| Phosphonic Acid SCHEMBL3614832 | 1.00 | — | — | |
| Phosphonic Acid SCHEMBL3138773 | 0.94 | — | — | |
| Phosphonic Acid SCHEMBL5137093 | 0.94 | — | — | |
| Phosphonic Acid SCHEMBL1872085 | 0.94 | — | — | |
| Phosphonic Acid SCHEMBL29436080 | 0.94 | — | — | |
| Phosphonic Acid SCHEMBL31144403 | 0.94 | — | — | |
| Phosphonic Acid SCHEMBL15573441 | 0.88 | — | — | |
| Phosphonic Acid SCHEMBL1325218 | 0.88 | — | — | |
| Phosphonic Acid SCHEMBL3556588 | 0.86 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111544655-B | Bisphosphonate type self-coagulation composite bone graft and preparation method thereof | 中鼎凯瑞科技成都有限公司 | 2022-06-24 | — | — | CN | claimed |
| CN-120040500-A | Soluble unsaturated double quaternary ammonium bisphosphonate | 江苏海洋大学 | 2025-05-27 | — | — | CN | disclosed |
| CN-115969813-A | Efficient and stable anionic polysaccharide calcium phosphate nanoparticle and preparation method and application thereof | 江南大学 | 2023-04-18 | — | — | CN | disclosed |
| CN-111544655-B | Bisphosphonate type self-coagulation composite bone graft and preparation method thereof | 中鼎凯瑞科技成都有限公司 | 2022-06-24 | — | — | CN | disclosed |
| CN-111544655-B | Bisphosphonate type self-coagulation composite bone graft and preparation method thereof | 中鼎凯瑞科技成都有限公司 | 2022-06-24 | — | — | CN | disclosed |
| CN-109930209-B | Bisphosphonate crystal with high crystallinity and length-diameter ratio and preparation method thereof | 华南理工大学 | 2022-02-15 | — | — | CN | disclosed |
| EP-2729180-B1 | METAL BISPHOSPHONATE NANOPARTICLES FOR ANTI-CANCER THERAPY AND IMAGING AND FOR TREATING BONE DISORDERS | UNIV NORTH CAROLINA CHAPEL HILL (US) | 2019-01-23 | — | — | EP | disclosed |
| EP-2493905-B1 | BISPHOSPHONATE COMPOUNDS FOR TREATING BONE METABOLISM DISORDERS | WARNER CHILCOTT CO LLC (PR) | 2016-11-30 | — | — | EP | disclosed |
| US-8822435-B2 | Bisphosphonate compounds | WARNER CHILCOTT COMPANY, LLC (US) | 2014-09-02 | — | — | US | disclosed |
| US-20140194389-A1 | BISPHOSPHONATE COMPOUNDS | WARNER CHILCOTT COMPANY, LLC (US) | 2014-07-10 | — | — | US | disclosed |
| US-8710215-B2 | Bisphosphonate compounds | WARNER CHILCOTT COMPANY, LLC (US) | 2014-04-29 | — | — | US | disclosed |
| US-20130035482-A1 | BISPHOSPHONATE COMPOUNDS | WARNER CHILCOTT COMPANY, LLC (US) | 2013-02-07 | — | — | US | disclosed |
| US-8314081-B2 | Bisphosphonate compounds | WARNER CHILCOTT COMPANY, LLC (US) | 2012-11-20 | — | — | US | disclosed |
| EP-2493905-A1 | BISPHOSPHONATE COMPOUNDS FOR TREATING BONE METABOLISM DISORDERS | Warner Chilcott Company, LLC (PR) | 2012-09-05 | — | — | EP | disclosed |
| WO-2011056589-A1 | BISPHOSPHONATE COMPOUNDS FOR TREATING BONE METABOLISM DISORDERS | WARNER CHILCOTT COMPANY, LLC (US) | 2011-05-12 | — | — | WO | disclosed |
| US-20110098251-A1 | BISPHOSPHONATE COMPOUNDS | WARNER CHILCOTT COMPANY, LLC (US) | 2011-04-28 | — | — | US | disclosed |
| US-6548042-B2 | Such as tetraethyl-N-(m-trimethylsilylphenylethyl)amino-methylenebisphosphonate for palliative and curative treatment of bone disorders and breast cancer | ARSTAD ERIK (NO) | 2003-04-15 | — | — | US | disclosed |
| US-20020042539-A1 | Bis-phosphonate compounds | ARSTAD ERIK (NO) | 2002-04-11 | — | — | US | disclosed |