SCHEMBL1665147

SCHEMBL1665147

CC(C)CNc1[c]c(NCC(C)C)ccc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 1/20 0.39
IDH1 O75874 1/20 0.38
KMT2A Q03164 3/20 0.37
GAA P10253 2/20 0.37
HSD17B10 Q99714 1/20 0.37
ESR1 P03372 5/20 0.36
ACP1 P24666 1/20 0.34
TLR7 Q9NYK1 2/20 0.33
MAPT P10636 2/20 0.33
KDM4E B2RXH2 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
HCAR3 P49019 1/20 0.33
HCAR2 Q8TDS4 1/20 0.33
LMNA P02545 1/20 0.33
KDM6B O15054 1/20 0.32
KDM4C Q9H3R0 1/20 0.32
MEN1 O00255 1/20 0.32
ALDH1A1 P00352 1/20 0.32
MAP4K4 O95819 1/20 0.31
GABRA1 P14867 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1666989 0.77 IDO1 (0.40) IDO1IDH1KMT2AGAAESR1
SCHEMBL1664974 0.76 ESR1 (0.39) IDO1IDH1ESR1MAPTL3MBTL1
SCHEMBL2067572 0.74 ESR1 (0.35) IDO1IDH1ESR1ACP1TLR7
SCHEMBL6249635 0.69 IDO1 (0.57) IDO1IDH1KMT2AGAAESR1
SCHEMBL27950619 0.68 MAPT (0.41) IDO1IDH1KMT2AGAAHSD17B10
SCHEMBL146034 0.67 IDO1 (0.45) IDO1IDH1GAAHSD17B10ESR1
SCHEMBL182877 0.67 MAPT (0.52) IDO1KMT2AHSD17B10ESR1ACP1
SCHEMBL14831229 0.67 KMT2A (0.42) IDO1IDH1KMT2AGAAHSD17B10
SCHEMBL1664327 0.66 ESR1 (0.35) IDO1ESR1
Iodide SCHEMBL29028129 0.65 MAPT (0.50) IDO1KMT2AHSD17B10ESR1ACP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7968019-B2 Optical compensation film, method for producing optical compensation film, polarization plate and liquid crystal display KONICA MINOLTA OPTO, INC. (JP) 2011-06-28 US disclosed
US-7922947-B2 Method of producing dispersion FUJIFILM CORPORATION (JP) 2011-04-12 US disclosed
US-7166339-B1 Phase contrast plate comprising one sheet of cellulose ester film containing aromatic compound FUJIFILM CORPORATION (JP) 2007-01-23 US disclosed
US-20060216437-A1 Optical compensation film, method for producing optical compensation film, polarization plate and liquid crystal display KONICA MINOLTA OPTO, INC. (JP) 2006-09-28 US disclosed
US-20050062193-A1 Method of producing dispersion FUJIFILM CORPORATION (JP) 2005-03-24 US disclosed
CN-1173198-C Phase retardation plate comprising cellulose ester film, circularly polarizing plate and liquid crystal display device 富士胶片株式会社 2004-10-27 CN disclosed
US-6630973-B1 Compensatory sheet, ellipsoidal polarizing plate and liquid crystal display. FUJI PHOTO FILM CO., LTD. (JP) 2003-10-07 US disclosed
CN-1348547-A Phase contrast plate comprising one sheet of cellulose ester film containing aromatic compound FUJI PHOTO FILM CO LTD (JP) 2002-05-08 CN disclosed
EP-1182470-A1 PHASE CONTRAST PLATE COMPRISING ONE SHEET OF CELLULOSE ESTER FILM CONTAINING AROMATIC COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 2002-02-27 EP disclosed