SCHEMBL1664327

SCHEMBL1664327

CC(C)CNc1[c]ccc(NCC(C)C)c1

nearest known ligand 0.35

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 5/20 0.35
AR P10275 2/20 0.35
PSEN1 P49768 1/20 0.34
PSEN2 P49810 1/20 0.34
APH1B Q8WW43 1/20 0.34
NCSTN Q92542 1/20 0.34
APH1A Q96BI3 1/20 0.34
PSENEN Q9NZ42 1/20 0.34
ITK Q08881 1/20 0.33
IDO1 P14902 1/20 0.31
APP P05067 1/20 0.31
HRH4 Q9H3N8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1664974 0.76 ESR1 (0.39) ESR1ARPSEN1PSEN2APH1B
SCHEMBL8945843 0.75 MAPT (0.33) AR
SCHEMBL1664353 0.74 ESR1 (0.36) ESR1ARPSEN1PSEN2APH1B
SCHEMBL8174902 0.74 PRSS1 (0.36)
SCHEMBL1666989 0.73 IDO1 (0.40) ESR1IDO1HRH4
SCHEMBL146034 0.70 IDO1 (0.45) ESR1ARPSEN1PSEN2APH1B
SCHEMBL592164 0.70
SCHEMBL1664153 0.66 ESR1 (0.41) ESR1ARPSEN1PSEN2APH1B
SCHEMBL1665147 0.66 IDO1 (0.39) ESR1IDO1
SCHEMBL1565326 0.65 HPGD (0.49) ESR1PSEN1PSEN2APH1BNCSTN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7968019-B2 Optical compensation film, method for producing optical compensation film, polarization plate and liquid crystal display KONICA MINOLTA OPTO, INC. (JP) 2011-06-28 US disclosed
US-7922947-B2 Method of producing dispersion FUJIFILM CORPORATION (JP) 2011-04-12 US disclosed
US-7166339-B1 Phase contrast plate comprising one sheet of cellulose ester film containing aromatic compound FUJIFILM CORPORATION (JP) 2007-01-23 US disclosed
US-20060216437-A1 Optical compensation film, method for producing optical compensation film, polarization plate and liquid crystal display KONICA MINOLTA OPTO, INC. (JP) 2006-09-28 US disclosed
US-20050062193-A1 Method of producing dispersion FUJIFILM CORPORATION (JP) 2005-03-24 US disclosed
CN-1173198-C Phase retardation plate comprising cellulose ester film, circularly polarizing plate and liquid crystal display device 富士胶片株式会社 2004-10-27 CN disclosed
US-6630973-B1 Compensatory sheet, ellipsoidal polarizing plate and liquid crystal display. FUJI PHOTO FILM CO., LTD. (JP) 2003-10-07 US disclosed
EP-1182470-A1 PHASE CONTRAST PLATE COMPRISING ONE SHEET OF CELLULOSE ESTER FILM CONTAINING AROMATIC COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 2002-02-27 EP disclosed