Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 1/20 | 0.50 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.50 |
| ▸ | CDK1 | P06493 | 4/20 | 0.45 |
| ▸ | CCNB1 | P14635 | 4/20 | 0.45 |
| ▸ | CCNA2 | P20248 | 4/20 | 0.45 |
| ▸ | CDK2 | P24941 | 4/20 | 0.45 |
| ▸ | CCNA1 | P78396 | 4/20 | 0.45 |
| ▸ | MGMT | P16455 | 3/20 | 0.45 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.44 |
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.44 |
| ▸ | POLA1 | P09884 | 1/20 | 0.40 |
| ▸ | XDH | P47989 | 4/20 | 0.39 |
| ▸ | PI4KA | P42356 | 2/20 | 0.39 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.39 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.39 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.39 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5144928 | 0.81 | XDH (0.56) | KDRAURKBCDK1CCNB1CCNA2 | |
| SCHEMBL4408536 | 0.76 | PDPK1 (0.56) | KDRAURKBCDK1CCNB1CCNA2 | |
| SCHEMBL29677204 | 0.76 | CDK2 (0.49) | KDRAURKBCDK1CCNB1CCNA2 | |
| SCHEMBL136630 | 0.76 | CDK2 (0.49) | KDRAURKBCDK1CCNB1CCNA2 | |
| SCHEMBL29728815 | 0.73 | PDPK1 (0.59) | KDRAURKBCDK1CCNB1CCNA2 | |
| SCHEMBL258583 | 0.73 | PDPK1 (0.59) | KDRAURKBCDK1CCNB1CCNA2 | |
| SCHEMBL11414191 | 0.72 | PDPK1 (0.51) | KDRAURKBCDK1CCNB1CCNA2 | |
| SCHEMBL8332129 | 0.71 | KDR (0.55) | KDRAURKBCDK2MGMTPDPK1 | |
| Phosphoric Acid SCHEMBL214567 | 0.71 | MGMT (0.44) | KDRAURKBCDK1CCNB1CCNA2 | |
| SCHEMBL25228360 | 0.70 | MGMT (0.43) | KDRAURKBCDK1CCNB1CCNA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2307565-A2 | NUCLEOTIDES AND NUCLEOSIDES AND METHODS FOR THEIR USE IN DNA SEQUENCING | Lasergen, Inc. (US) | 2011-04-13 | — | — | EP | disclosed |
| WO-2009152353-A2 | NUCLEOTIDES AND NUCLEOSIDES AND METHODS FOR THEIR USE IN DNA SEQUENCING | LASERGEN, INC. (US) | 2009-12-17 | — | — | WO | disclosed |