Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 1/20 | 0.56 |
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.56 |
| ▸ | KDR | P35968 | 1/20 | 0.53 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.53 |
| ▸ | CDK1 | P06493 | 11/20 | 0.48 |
| ▸ | CCNB1 | P14635 | 11/20 | 0.48 |
| ▸ | CCNA2 | P20248 | 10/20 | 0.48 |
| ▸ | CDK2 | P24941 | 10/20 | 0.48 |
| ▸ | CCNA1 | P78396 | 10/20 | 0.48 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.47 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.45 |
| ▸ | PI4KA | P42356 | 2/20 | 0.44 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.44 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.44 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | XDH | P47989 | 1/20 | 0.44 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.44 |
| ▸ | POLA1 | P09884 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5144928 | 0.83 | XDH (0.56) | PDPK1GDAKDRAURKBCDK1 | |
| SCHEMBL258583 | 0.83 | PDPK1 (0.59) | PDPK1GDAKDRAURKBCDK1 | |
| SCHEMBL29728815 | 0.83 | PDPK1 (0.59) | PDPK1GDAKDRAURKBCDK1 | |
| SCHEMBL11414191 | 0.80 | PDPK1 (0.51) | PDPK1GDAKDRAURKBCDK1 | |
| SCHEMBL1330116 | 0.79 | PDPK1 (0.54) | PDPK1GDAKDRAURKBCDK1 | |
| SCHEMBL8332129 | 0.78 | KDR (0.55) | PDPK1GDAKDRAURKBCDK2 | |
| SCHEMBL1665221 | 0.76 | KDR (0.50) | PDPK1GDAKDRAURKBCDK1 | |
| SCHEMBL29592683 | 0.76 | PDPK1 (0.59) | PDPK1GDACDK1CCNB1CCNA2 | |
| SCHEMBL1924592 | 0.76 | PDPK1 (0.59) | PDPK1GDACDK1CCNB1CCNA2 | |
| SCHEMBL16758710 | 0.75 | MAP3K5 (0.69) | PDPK1GDACDK1CCNB1CCNA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090131651-A1 | Synthesis of 2-substituted adenosines | CBT DEVELOPMENT LIMITED (GB) | 2009-05-21 | — | — | US | disclosed |
| US-20080262214-A1 | Synthesis of 2-Substituted Adenosines | CAMBRIDGE BIOTECHNOLOGY LIMITED (GB) | 2008-10-23 | — | — | US | disclosed |
| EP-1697393-A1 | IMPROVED SYNTHESIS OF 2-SUBSTITUTED ADENOSINES | BIOVITRUM AB (SE) | 2006-09-06 | — | — | EP | disclosed |
| EP-1694691-A1 | IMPROVED SYNTHESIS OF 2-SUBSTITUTED ADENOSINES | BIOVITRUM AB (SE) | 2006-08-30 | — | — | EP | disclosed |
| WO-2005056571-A1 | IMPROVED SYNTHESIS OF 2-SUBSTITUTED ADENOSINES | BIOVITRUM AB (SE) | 2005-06-23 | — | — | WO | disclosed |
| WO-2005054269-A1 | IMPROVED SYNTHESIS OF 2-SUBSTITUTED ADENOSINES | BIOVITRUM AB (SE) | 2005-06-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080262214-A1 | Synthesis of 2-Substituted Adenosines | ADORA3, ADORA1, ADORA2A | PDPK1 3562/4885GDA 184/4885KDR 2868/4885 |
| US-20090131651-A1 | Synthesis of 2-substituted adenosines | ADORA3, NT5C2, RNGTT | PDPK1 3552/4885GDA 100/4885KDR 3616/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.