Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.38 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | MAT2A | P31153 | 2/20 | 0.32 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.31 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16653075 | 0.91 | DGAT1 (0.37) | DGAT1AGTR1KMT2AKDM4ENPC1 | |
| SCHEMBL15357238 | 0.90 | DGAT1 (0.37) | DGAT1KMT2ANPC1RAB9ATP53 | |
| SCHEMBL16652916 | 0.89 | DGAT1 (0.37) | DGAT1AGTR1KMT2AKDM4ENPC1 | |
| SCHEMBL14904598 | 0.89 | DGAT1 (0.40) | DGAT1KMT2AKDM4ENPC1RAB9A | |
| SCHEMBL16652575 | 0.88 | DGAT1 (0.37) | DGAT1AGTR1KMT2AKDM4ENPC1 | |
| SCHEMBL16652258 | 0.88 | DGAT1 (0.37) | DGAT1AGTR1KMT2AKDM4ENPC1 | |
| SCHEMBL4970225 | 0.87 | NPC1 (0.38) | DGAT1AGTR1KMT2AKDM4ENPC1 | |
| SCHEMBL15346722 | 0.87 | DGAT1 (0.38) | DGAT1KMT2AKDM4ENPC1RAB9A | |
| SCHEMBL15975709 | 0.87 | DGAT1 (0.39) | DGAT1KMT2AKDM4ENPC1RAB9A | |
| SCHEMBL15357116 | 0.86 | DGAT1 (0.41) | DGAT1KMT2AKDM4ENPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9523100-B2 | Pesticidal compositions and related methods | DOW AGROSCIENCES LLC (US) | 2016-12-20 | — | — | US | disclosed |
| US-9523100-B2 | Pesticidal compositions and related methods | DOW AGROSCIENCES LLC (US) | 2016-12-20 | — | — | US | disclosed |
| US-9523100-B2 | Pesticidal compositions and related methods | DOW AGROSCIENCES LLC (US) | 2016-12-20 | — | — | US | disclosed |
| US-20160208281-A1 | PESTICIDAL COMPOSITIONS AND RELATED METHODS | DOW AGROSCIENCES LLC | 2016-07-21 | — | — | US | disclosed |
| US-20160208281-A1 | PESTICIDAL COMPOSITIONS AND RELATED METHODS | DOW AGROSCIENCES LLC | 2016-07-21 | — | — | US | disclosed |
| US-20160208281-A1 | PESTICIDAL COMPOSITIONS AND RELATED METHODS | DOW AGROSCIENCES LLC | 2016-07-21 | — | — | US | disclosed |
| US-9295260-B2 | Pesticidal compositions and related methods | DOW AGROSCIENCES LLC (US) | 2016-03-29 | — | — | US | disclosed |
| US-9295260-B2 | Pesticidal compositions and related methods | DOW AGROSCIENCES LLC (US) | 2016-03-29 | — | — | US | disclosed |
| US-9295260-B2 | Pesticidal compositions and related methods | DOW AGROSCIENCES LLC (US) | 2016-03-29 | — | — | US | disclosed |
| WO-2015061165-A1 | PESTICIDAL COMPOSITIONS AND RELATED METHODS | DOW AGROSCIENCES LLC (US) | 2015-04-30 | — | — | WO | disclosed |
| US-20150111734-A1 | PESTICIDAL COMPOSITIONS AND RELATED METHODS | DOW AGROSCIENCES LLC | 2015-04-23 | — | — | US | disclosed |
| US-20150111734-A1 | PESTICIDAL COMPOSITIONS AND RELATED METHODS | DOW AGROSCIENCES LLC | 2015-04-23 | — | — | US | disclosed |
| US-20150111734-A1 | PESTICIDAL COMPOSITIONS AND RELATED METHODS | DOW AGROSCIENCES LLC | 2015-04-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160208281-A1 | PESTICIDAL COMPOSITIONS AND RELATED METHODS | ACHE, RDX, PRDX1 | DGAT1 3968/4885AGTR1 1105/4885KMT2A 1020/4885 |
| US-20150111734-A1 | PESTICIDAL COMPOSITIONS AND RELATED METHODS | ACHE, RDX, CHRM2 | DGAT1 3804/4885AGTR1 1059/4885KMT2A 1155/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.