Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Vernolate SCHEMBL55115 | 0.82 | TSHR (0.71) | TSHRMAPK1ALDH1A1HPGDTDP1 | |
| Vernolate SCHEMBL8538253 | 0.82 | TSHR (0.71) | TSHRMAPK1ALDH1A1HPGDTDP1 | |
| SCHEMBL11180981 | 0.75 | TSHR (0.59) | TSHRMAPK1ALDH1A1HPGDTDP1 | |
| Vernolate SCHEMBL11547988 | 0.74 | TSHR (0.59) | TSHRMAPK1ALDH1A1HPGDTDP1 | |
| Vernolate SCHEMBL10749396 | 0.73 | TSHR (0.57) | TSHRMAPK1ALDH1A1HPGDTDP1 | |
| SCHEMBL10718303 | 0.71 | TSHR (0.65) | TSHRMAPK1ALDH1A1HPGDTDP1 | |
| S-Ethyl Dipropylcarbamothioate SCHEMBL8541416 | 0.68 | TSHR (1.00) | TSHRMAPK1ALDH1A1HPGDTDP1 | |
| S-Ethyl Dipropylcarbamothioate SCHEMBL66482 | 0.68 | TSHR (1.00) | TSHRMAPK1ALDH1A1HPGDTDP1 | |
| SCHEMBL21221408 | 0.68 | TSHR (0.74) | TSHRMAPK1ALDH1A1HPGDTDP1 | |
| SCHEMBL9420118 | 0.68 | ALDH1A1 (0.49) | TSHRMAPK1ALDH1A1HPGDTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190216895-A1 | BOLAAMPHIPHILIC COMPOUNDS, COMPOSITIONS AND USES THEREOF | LAUREN SCIENCES LLC (US) | 2019-07-18 | — | — | US | disclosed |
| US-20160367678-A1 | BOLAAMPHIPHILIC COMPOUNDS, COMPOSITIONS AND USES THEREOF | LAUREN SCIENCES LLC (US) | 2016-12-22 | — | — | US | disclosed |
| US-20150110875-A1 | BOLAAMPHIPHILIC COMPOUNDS, COMPOSITIONS AND USES THEREOF | LAUREN SCIENCES LLC (US) | 2015-04-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190216895-A1 | BOLAAMPHIPHILIC COMPOUNDS, COMPOSITIONS AND USES THEREOF | GFRA2, GFRA1, NGF | TSHR 2965/4885MAPK1 1419/4885ALDH1A1 133/4885 |
| US-20160367678-A1 | BOLAAMPHIPHILIC COMPOUNDS, COMPOSITIONS AND USES THEREOF | GFRA2, GFRA1, NGF | TSHR 2742/4885MAPK1 1316/4885ALDH1A1 148/4885 |
| US-20150110875-A1 | BOLAAMPHIPHILIC COMPOUNDS, COMPOSITIONS AND USES THEREOF | GFRA2, GFRA1, NGF | TSHR 2921/4885MAPK1 1462/4885ALDH1A1 137/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.