Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCAT2 | O15382 | 1/20 | 0.50 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.48 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.48 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.48 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.48 |
| ▸ | GRM5 | P41594 | 2/20 | 0.47 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.47 |
| ▸ | FEN1 | P39748 | 1/20 | 0.47 |
| ▸ | CTSA | P10619 | 2/20 | 0.46 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.46 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TGFBR2 | P37173 | 1/20 | 0.45 |
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CDC7 | O00311 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10489526 | 0.83 | BCAT2 (0.51) | BCAT2KDM4CCSNK1A1TYRO3DYRK1B | |
| SCHEMBL29974939 | 0.83 | BCAT2 (0.51) | BCAT2KDM4CCSNK1A1TYRO3DYRK1B | |
| SCHEMBL28180027 | 0.81 | BCAT2 (0.50) | BCAT2KDM4CCSNK1A1TYRO3DYRK1B | |
| SCHEMBL16654017 | 0.81 | KDM4C (0.51) | BCAT2KDM4CCSNK1A1TYRO3DYRK1B | |
| SCHEMBL1968501 | 0.81 | BCAT2 (0.46) | BCAT2KDM4CCSNK1A1TYRO3DYRK1B | |
| SCHEMBL31249988 | 0.78 | GRM5 (0.64) | BCAT2CSNK1A1TYRO3DYRK1BGRM5 | |
| SCHEMBL31249984 | 0.78 | GRM5 (0.64) | BCAT2CSNK1A1TYRO3DYRK1BGRM5 | |
| SCHEMBL29506339 | 0.78 | GRM5 (0.64) | BCAT2CSNK1A1TYRO3DYRK1BGRM5 | |
| SCHEMBL997865 | 0.78 | GRM5 (0.64) | BCAT2CSNK1A1TYRO3DYRK1BGRM5 | |
| SCHEMBL16654039 | 0.78 | KDM4C (0.48) | BCAT2KDM4CCSNK1A1TYRO3DYRK1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4006035-B1 | QUINAZOLINE DERIVATIVES AS TYROSINE KINASE INHIBITORS FOR THE TREATMENT OF CANCER | NEUPHARMA INC (US) | 2023-11-22 | — | — | EP | disclosed |
| WO-2015057992-A1 | BTK INHIBITORS FOR HEMATOPOIETIC MOBILIZATION | IZUMI RAQUEL (US) | 2015-04-23 | — | — | WO | disclosed |