Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7692047 | 0.79 | TSHR (0.59) | TSHRTP53THRBTRPM8KMT2A | |
| SCHEMBL6316045 | 0.78 | TSHR (0.58) | TSHRTP53THRBKMT2ANPC1 | |
| SCHEMBL18825315 | 0.78 | HTT (0.40) | TP53KMT2ANPC1RAB9AHSD17B10 | |
| SCHEMBL6796283 | 0.77 | TSHR (0.50) | TSHRTP53THRBTRPM8KMT2A | |
| SCHEMBL6778056 | 0.77 | KMT2A (0.56) | TSHRKMT2ANPC1RAB9AHTT | |
| SCHEMBL14636838 | 0.77 | TP53 (0.46) | TSHRTP53THRBPOLBALDH1A1 | |
| SCHEMBL17675195 | 0.76 | TSHR (0.59) | TSHRTP53THRBTRPM8KMT2A | |
| SCHEMBL5225088 | 0.76 | TSHR (0.59) | TSHRTP53THRBTRPM8KMT2A | |
| SCHEMBL4526462 | 0.75 | HPGD (0.50) | TSHRKMT2ANPC1RAB9AHTT | |
| SCHEMBL10840731 | 0.75 | TSHR (0.58) | TSHRTP53THRBTRPM8KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015057992-A1 | BTK INHIBITORS FOR HEMATOPOIETIC MOBILIZATION | IZUMI RAQUEL (US) | 2015-04-23 | — | — | WO | disclosed |