Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.44 |
| ▸ | PLOD3 | O60568 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | PLOD1 | Q02809 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
| ▸ | TYK2 | P29597 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4526462 | 0.89 | HPGD (0.50) | KMT2AKDM4EALDH1A1HPGDL3MBTL1 | |
| SCHEMBL31606638 | 0.81 | HPGD (0.41) | KMT2AKDM4EMEN1HSP90AA1ALDH1A1 | |
| SCHEMBL11410329 | 0.78 | KDM4E (0.44) | KMT2AKDM4EMEN1HSP90AA1HPGD | |
| SCHEMBL13479892 | 0.78 | LMNA (0.48) | KMT2AKDM4EALDH1A1HPGDCYP1A2 | |
| SCHEMBL30587712 | 0.78 | OXTR (0.42) | KMT2AKDM4EALDH1A1HPGDTSHR | |
| SCHEMBL16654075 | 0.77 | TSHR (0.54) | KMT2AKDM4EALDH1A1POLBTSHR | |
| SCHEMBL12103690 | 0.77 | KMT2A (0.56) | KMT2AKDM4EMEN1HSP90AA1ALDH1A1 | |
| Pyrazine SCHEMBL28474766 | 0.76 | KMT2A (0.47) | KMT2AKDM4EMEN1HSP90AA1ALDH1A1 | |
| SCHEMBL13723635 | 0.74 | PBRM1 (0.51) | KMT2AKDM4EMEN1ALDH1A1HPGD | |
| SCHEMBL27764304 | 0.74 | JAK2 (0.49) | KMT2AKDM4EMEN1HSP90AA1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6780883-B2 | ANTICHOLESTEROL AGENTS; CARDIOVASCULAR DISORDERS; ANTILIPEMIC AGENTS; RESTENOSIS; DIETETICS | WARNER-LAMBERT COMPANY | 2004-08-24 | — | — | US | disclosed |