Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.31 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9952467 | 1.00 | KMT2A (0.33) | KMT2AMEN1RAPGEF4HSP90AA1IRAK4 | |
| SCHEMBL30533221 | 1.00 | KMT2A (0.33) | KMT2AMEN1RAPGEF4HSP90AA1IRAK4 | |
| Hydrochloric Acid SCHEMBL1952792 | 0.99 | MEN1 (0.32) | KMT2AMEN1RAPGEF4HSP90AA1IRAK4 | |
| SCHEMBL30533220 | 0.99 | MEN1 (0.32) | KMT2AMEN1RAPGEF4HSP90AA1IRAK4 | |
| SCHEMBL1120701 | 0.98 | KMT2A (0.33) | KMT2AMEN1RAPGEF4HSP90AA1IRAK4 | |
| SCHEMBL1120699 | 0.98 | KMT2A (0.33) | KMT2AMEN1RAPGEF4HSP90AA1IRAK4 | |
| SCHEMBL29558324 | 0.98 | KMT2A (0.33) | KMT2AMEN1RAPGEF4HSP90AA1IRAK4 | |
| SCHEMBL4531342 | 0.97 | KMT2A (0.33) | KMT2AMEN1RAPGEF4HSP90AA1IRAK4 | |
| SCHEMBL4531344 | 0.97 | KMT2A (0.33) | KMT2AMEN1RAPGEF4HSP90AA1IRAK4 | |
| SCHEMBL31013359 | 0.97 | KMT2A (0.33) | KMT2AMEN1RAPGEF4HSP90AA1IRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3058002-A1 | POLYETHYLENE OF RAISED TEMPERATURE RESISTANCE | Basell Polyolefine GmbH (DE) | 2016-08-24 | — | — | EP | disclosed |
| WO-2015055392-A1 | POLYETHYLENE OF RAISED TEMPERATURE RESISTANCE | BASELL POLYOLEFINE GMBH (DE) | 2015-04-23 | — | — | WO | disclosed |