Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.31 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4531342 | 1.00 | KMT2A (0.33) | KMT2AMEN1RAPGEF4HSP90AA1IRAK4 | |
| SCHEMBL30533220 | 0.99 | MEN1 (0.32) | KMT2AMEN1RAPGEF4HSP90AA1IRAK4 | |
| SCHEMBL1120699 | 0.98 | KMT2A (0.33) | KMT2AMEN1RAPGEF4HSP90AA1IRAK4 | |
| SCHEMBL1120701 | 0.98 | KMT2A (0.33) | KMT2AMEN1RAPGEF4HSP90AA1IRAK4 | |
| SCHEMBL29558324 | 0.98 | KMT2A (0.33) | KMT2AMEN1RAPGEF4HSP90AA1IRAK4 | |
| SCHEMBL4515332 | 0.97 | MEN1 (0.35) | KMT2AMEN1RAPGEF4HSP90AA1ATM | |
| SCHEMBL4515328 | 0.97 | MEN1 (0.35) | KMT2AMEN1RAPGEF4HSP90AA1ATM | |
| SCHEMBL9952467 | 0.97 | KMT2A (0.33) | KMT2AMEN1RAPGEF4HSP90AA1IRAK4 | |
| SCHEMBL16654076 | 0.97 | KMT2A (0.33) | KMT2AMEN1RAPGEF4HSP90AA1IRAK4 | |
| SCHEMBL31013359 | 0.97 | KMT2A (0.33) | KMT2AMEN1RAPGEF4HSP90AA1IRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1971577-B1 | Process for the preparation of unsymmetric bis(imino) compounds | BASELL POLYOLEFINE GMBH (DE) | 2014-11-26 | — | — | EP | disclosed |
| US-8252875-B2 | Process for the preparation of unsymmetric bis(imino) compounds | BASELL POLYOLEFINE GMBH (DE) | 2012-08-28 | — | — | US | disclosed |
| US-20090054609-A1 | Process for the Preparation of Unsymmetric Bis(Imino) Compounds | BASELL POLYOLEFINE GMBH (DE) | 2009-02-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090054609-A1 | Process for the Preparation of Unsymmetric Bis(Imino) Compounds | FHIT, OAT, NONO | KMT2A 1845/4885MEN1 1919/4885RAPGEF4 3860/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.