SCHEMBL1120699

SCHEMBL1120699

C/C(=N\c1c(C)cc(C)cc1Cl)c1cccc(/C(C)=N/c2c(C)cc(C)cc2Cl)n1

nearest known ligand 0.39

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.33
MEN1 O00255 3/20 0.33
RAPGEF4 Q8WZA2 1/20 0.33
HSP90AA1 P07900 2/20 0.32
IRAK4 Q9NWZ3 1/20 0.31
ATM Q13315 1/20 0.31
RAB9A P51151 2/20 0.31
KDM4E B2RXH2 1/20 0.31
NPC1 O15118 1/20 0.31
LMNA P02545 1/20 0.31
ALDH1A1 P00352 1/20 0.30
PAX8 Q06710 1/20 0.30
CRHR1 P34998 1/20 0.30
DHODH Q02127 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29558324 1.00 KMT2A (0.33) KMT2AMEN1RAPGEF4HSP90AA1IRAK4
SCHEMBL1120701 1.00 KMT2A (0.33) KMT2AMEN1RAPGEF4HSP90AA1IRAK4
SCHEMBL4531344 0.98 KMT2A (0.33) KMT2AMEN1RAPGEF4HSP90AA1IRAK4
SCHEMBL30533221 0.98 KMT2A (0.33) KMT2AMEN1RAPGEF4HSP90AA1IRAK4
SCHEMBL9952467 0.98 KMT2A (0.33) KMT2AMEN1RAPGEF4HSP90AA1IRAK4
SCHEMBL4531342 0.98 KMT2A (0.33) KMT2AMEN1RAPGEF4HSP90AA1IRAK4
SCHEMBL16654076 0.98 KMT2A (0.33) KMT2AMEN1RAPGEF4HSP90AA1IRAK4
SCHEMBL31013359 0.98 KMT2A (0.33) KMT2AMEN1RAPGEF4HSP90AA1IRAK4
Hydrochloric Acid SCHEMBL3625061 0.97 KMT2A (0.32) KMT2AMEN1RAPGEF4HSP90AA1IRAK4
Hydrochloric Acid SCHEMBL1952792 0.97 MEN1 (0.32) KMT2AMEN1RAPGEF4HSP90AA1IRAK4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 123 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230322972-A1 Supported Catalyst Systems and Processes for Use Thereof EXXONMOBIL CHEMICAL PATENTS INC (US) 2023-10-12 US disclosed
US-20230322972-A1 Supported Catalyst Systems and Processes for Use Thereof EXXONMOBIL CHEMICAL PATENTS INC (US) 2023-10-12 US disclosed
US-20230322972-A1 Supported Catalyst Systems and Processes for Use Thereof EXXONMOBIL CHEMICAL PATENTS INC (US) 2023-10-12 US disclosed
WO-2023177957-A1 METAL-CONTAINING BIS(IMINO) PER-SUBSTITUTED ARYL COMPOUNDS AND METHODS THEREOF EXXONMOBIL CHEMICAL PATENTS INC. (US) 2023-09-21 WO disclosed
US-11738334-B2 Supported catalyst systems and processes for use thereof EXXONMOBIL CHEMICAL PATENTS INC. (US) 2023-08-29 US disclosed
US-11738334-B2 Supported catalyst systems and processes for use thereof EXXONMOBIL CHEMICAL PATENTS INC. (US) 2023-08-29 US disclosed
US-11718635-B2 Iron bis(imino) aryl catalysts and methods thereof EXXONMOBIL CHEMICAL PATENTS INC. (US) 2023-08-08 US disclosed
US-11718635-B2 Iron bis(imino) aryl catalysts and methods thereof EXXONMOBIL CHEMICAL PATENTS INC. (US) 2023-08-08 US disclosed
US-11712687-B2 Catalyst systems and polymerization processes for using the same EXXONMOBIL CHEMICAL PATENTS INC. (US) 2023-08-01 US disclosed
US-11712687-B2 Catalyst systems and polymerization processes for using the same EXXONMOBIL CHEMICAL PATENTS INC. (US) 2023-08-01 US disclosed
US-20090306299-A1 Multimodal polyethylene composition, mixed catalyst and process for preparing the composition BASELL POLYOLEFINE GMBH (DE) 2009-12-10 US disclosed
EP-2102282-A2 MULTIMODAL POLYETHYLENE COMPOSITION, MIXED CATALYST AND PROCESS FOR PREPARING THE COMPOSITION Basell Polyolefine GmbH (DE) 2009-09-23 EP disclosed
US-20090118445-A1 Hybrid Catalyst Systems Supported On Magnesium Halide BASELL POLYOLOLINE GMBH (DE) 2009-05-07 US disclosed
US-20090118445-A1 Hybrid Catalyst Systems Supported On Magnesium Halide BASELL POLYOLOLINE GMBH (DE) 2009-05-07 US disclosed
US-20090054609-A1 Process for the Preparation of Unsymmetric Bis(Imino) Compounds BASELL POLYOLEFINE GMBH (DE) 2009-02-26 US disclosed
WO-2008132059-A1 POLYETHYLENE, PROCESS AND CATALYST COMPOSITION FOR THE PREPARATION THEREOF BASELL POLYOLEFINE GMBH (DE) 2008-11-06 WO disclosed
WO-2008107135-A1 IRON COMPLEXES AND THEIR USE IN POLYMERIZATION PROCESSES BASELL POLYOLEFINE GMBH (DE) 2008-09-12 WO disclosed
EP-1943281-A1 HYBRID CATALYST SYSTEMS SUPPORTED ON MAGNESIUM HALIDE Basell Polyolefine GmbH (DE) 2008-07-16 EP disclosed
WO-2008077530-A2 MULTIMODAL POLYETHYLENE COMPOSITION, MIXED CATALYST AND PROCESS FOR PREPARING THE COMPOSITION BASELL POLYOLEFINE GMBH (DE) 2008-07-03 WO disclosed
WO-2007042252-A1 HYBRID CATALYST SYSTEMS SUPPORTED ON MAGNESIUM HALIDE BASELL POLYOLEFINE GMBH (DE) 2007-04-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090054609-A1 Process for the Preparation of Unsymmetric Bis(Imino) Compounds FHIT, OAT, NONO KMT2A 1845/4885MEN1 1919/4885RAPGEF4 3860/4885
US-11718635-B2 Iron bis(imino) aryl catalysts and methods thereof IDO2, SLC40A1, IDO1 KMT2A 1685/4885MEN1 1112/4885RAPGEF4 2570/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.