SCHEMBL9952467

SCHEMBL9952467

CC(=Nc1c(C)cc(C)cc1Cl)c1cccc(C(C)=Nc2c(C)cc(C)cc2Cl)n1.[Fe]

nearest known ligand 0.38

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.33
MEN1 O00255 3/20 0.33
RAPGEF4 Q8WZA2 1/20 0.32
HSP90AA1 P07900 2/20 0.31
IRAK4 Q9NWZ3 1/20 0.31
RAB9A P51151 2/20 0.30
ATM Q13315 1/20 0.30
KDM4E B2RXH2 1/20 0.30
NPC1 O15118 1/20 0.30
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16654076 1.00 KMT2A (0.33) KMT2AMEN1RAPGEF4HSP90AA1IRAK4
SCHEMBL30533221 1.00 KMT2A (0.33) KMT2AMEN1RAPGEF4HSP90AA1IRAK4
Hydrochloric Acid SCHEMBL1952792 0.99 MEN1 (0.32) KMT2AMEN1RAPGEF4HSP90AA1IRAK4
SCHEMBL30533220 0.99 MEN1 (0.32) KMT2AMEN1RAPGEF4HSP90AA1IRAK4
SCHEMBL1120701 0.98 KMT2A (0.33) KMT2AMEN1RAPGEF4HSP90AA1IRAK4
SCHEMBL1120699 0.98 KMT2A (0.33) KMT2AMEN1RAPGEF4HSP90AA1IRAK4
SCHEMBL29558324 0.98 KMT2A (0.33) KMT2AMEN1RAPGEF4HSP90AA1IRAK4
SCHEMBL4531342 0.97 KMT2A (0.33) KMT2AMEN1RAPGEF4HSP90AA1IRAK4
SCHEMBL4531344 0.97 KMT2A (0.33) KMT2AMEN1RAPGEF4HSP90AA1IRAK4
SCHEMBL31013359 0.97 KMT2A (0.33) KMT2AMEN1RAPGEF4HSP90AA1IRAK4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2760958-B1 SYSTEMS, METHODS AND COMPOSITIONS FOR PRODUCTION OF TIE-LAYER ADHESIVES EQUISTAR CHEM LP (US) 2020-08-12 EP claimed
US-9676971-B2 Systems, methods and compositions for production of tie-layer adhesives EQUISTAR CHEMICALS, LP (US) 2017-06-13 US claimed
US-9321945-B2 Systems, methods and compositions for production of tie-layer adhesives EQUISTAR CHEMICALS, LP (US) 2016-04-26 US claimed
US-9000113-B2 Polyethylene composition and method for obtaining same BASELL POLYOLEFINE GMBH (DE) 2015-04-07 US claimed
CN-114729167-B Polyethylene composition for filaments or fibres 巴塞尔聚烯烃股份有限公司 2023-09-26 CN disclosed
CN-115850552-A Catalyst system and polymerization process using the same 埃克森美孚化学专利公司 2023-03-28 CN disclosed
CN-111433229-B Catalyst system and polymerization process using the same 埃克森美孚化学专利公司 2022-12-13 CN disclosed
CN-114729167-A Polyethylene composition for filaments or fibres 巴塞尔聚烯烃股份有限公司 2022-07-08 CN disclosed
CN-111212857-B Hybrid catalyst with 2, 6-bis (imino) pyridinyliron complex and bridged hafnocene 埃克森美孚化学专利公司 2022-06-24 CN disclosed
CN-114641526-A Polyethylene composition for filaments or fibres 巴塞尔聚烯烃股份有限公司 2022-06-17 CN disclosed
CN-112250937-A Polyethylene composition for injection moulding 巴塞尔聚烯烃股份有限公司 2021-01-22 CN disclosed
EP-2760958-B1 SYSTEMS, METHODS AND COMPOSITIONS FOR PRODUCTION OF TIE-LAYER ADHESIVES EQUISTAR CHEM LP (US) 2020-08-12 EP disclosed
CN-111433229-A Catalyst system and polymerization process using the same 埃克森美孚化学专利公司 2020-07-17 CN disclosed
EP-3661984-A1 FILMS MADE FROM POLYETHYLENE COMPOSITIONS AND PROCESSES FOR MAKING THE SAME ExxonMobil Chemical Patents Inc. (US) 2020-06-10 EP disclosed
CN-111212857-A Hybrid catalyst with 2, 6-bis (imino) pyridinyliron complex and bridged hafnocene 埃克森美孚化学专利公司 2020-05-29 CN disclosed
CN-110982164-A Polyethylene for injection moulding 巴塞尔聚烯烃股份有限公司 2020-04-10 CN disclosed
WO-2019027605-A1 FILMS MADE FROM POLYETHYLENE COMPOSITIONS AND PROCESSES FOR MAKING THE SAME EXXONMOBIL CHEMICAL PATENTS INC. (US) 2019-02-07 WO disclosed
EP-2655445-A1 PROCESS FOR CONTROLLING THE RELATIVE ACTIVITY OF ACTIVE CENTERS OF CATALYST SYSTEMS COMPRISING AT LEAST ONE LATE TRANSITION METAL CATALYST COMPONENT AND AT LEAST ONE ZIEGLER CATALYST COMPONENT Basell Polyolefine GmbH (DE) 2013-10-30 EP disclosed
WO-2012084774-A1 PROCESS FOR CONTROLLING THE RELATIVE ACTIVITY OF ACTIVE CENTERS OF CATALYST SYSTEMS COMPRISING AT LEAST ONE LATE TRANSITION METAL CATALYST COMPONENT AND AT LEAST ONE ZIEGLER CATALYST COMPONENT BASELL POLYOLEFINE GMBH (DE) 2012-06-28 WO disclosed