Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ILK | Q13418 | 2/20 | 0.56 |
| ▸ | AGPAT2 | O15120 | 3/20 | 0.49 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MGAM | O43451 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SI | P14410 | 1/20 | 0.37 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.37 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.37 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.37 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NSD2 | O96028 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7259223 | 0.74 | AGPAT2 (0.60) | ILKAGPAT2DYRK1AHSD17B10GAA | |
| SCHEMBL27557191 | 0.74 | ILK (0.59) | ILKAGPAT2DYRK1AHSD17B10MGAM | |
| SCHEMBL6691854 | 0.72 | AGPAT2 (0.46) | ILKAGPAT2DYRK1AAKR1B1AKR1A1 | |
| SCHEMBL1666264 | 0.72 | ILK (0.56) | ILKAGPAT2DYRK1A | |
| SCHEMBL12057939 | 0.71 | ILK (0.59) | ILKAGPAT2DYRK1AGAAAKR1B1 | |
| SCHEMBL12471082 | 0.70 | KDM4E (0.62) | ILKAGPAT2DYRK1AMGAMGAA | |
| SCHEMBL687301 | 0.70 | ILK (0.64) | ILKAGPAT2DYRK1AGAAMEN1 | |
| SCHEMBL777758 | 0.70 | DYRK1A (0.52) | ILKAGPAT2DYRK1AAKR1B1AKR1A1 | |
| SCHEMBL7263929 | 0.70 | AGPAT2 (0.58) | ILKAGPAT2DYRK1AHSD17B10MEN1 | |
| SCHEMBL12470403 | 0.69 | ILK (0.56) | ILKAGPAT2DYRK1AHSD17B10MGAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2486035-A1 | HETEROCYCLIC COMPOUND AND ITS USE FOR CONTROL OF AN ARTHROPOD PEST | Sumitomo Chemical Co., Ltd (JP) | 2012-08-15 | — | — | EP | disclosed |
| WO-2011043404-A1 | HETEROCYCLIC COMPOUND AND ITS USE FOR CONTROL OF AN ARTHROPOD PEST | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-04-14 | — | — | WO | disclosed |