Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGPAT2 | O15120 | 3/20 | 0.46 |
| ▸ | ILK | Q13418 | 2/20 | 0.44 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.37 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.37 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.37 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.37 |
| ▸ | MAT2A | P31153 | 1/20 | 0.36 |
| ▸ | NCS1 | P62166 | 1/20 | 0.35 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
| ▸ | RORB | Q92753 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | STK10 | O94804 | 1/20 | 0.34 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.34 |
| ▸ | EIF4E | P06730 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.34 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2138665 | 0.73 | ILK (0.54) | AGPAT2ILKDYRK1AL3MBTL1 | |
| SCHEMBL1884283 | 0.72 | AGPAT2 (0.44) | AGPAT2ILKAKR1B1DYRK1AAKR1B10 | |
| SCHEMBL1665435 | 0.72 | ILK (0.56) | AGPAT2ILKAKR1B1DYRK1AL3MBTL1 | |
| SCHEMBL6691852 | 0.70 | AGPAT2 (0.44) | AGPAT2ILKMAT2AAKR1B1DYRK1A | |
| SCHEMBL11011940 | 0.69 | ILK (0.52) | AGPAT2ILKNCS1AKR1B1DYRK1A | |
| SCHEMBL12470403 | 0.69 | ILK (0.56) | AGPAT2ILKNCS1DYRK1AL3MBTL1 | |
| SCHEMBL3667347 | 0.68 | MAPK14 (0.42) | — | |
| SCHEMBL7259223 | 0.68 | AGPAT2 (0.60) | AGPAT2ILKDYRK1AL3MBTL1 | |
| SCHEMBL7263929 | 0.66 | AGPAT2 (0.58) | AGPAT2ILKDYRK1AEIF4E | |
| SCHEMBL1666264 | 0.66 | ILK (0.56) | AGPAT2ILKDYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1465626-A2 | PHARMACEUTICAL COMPOSITIONS COMPRISING DIHYDROPYRIDINONE COMPOUNDS AND AN IMMUNOREGULATORY OR AN ANTIINFLAMMATORY AGENT AND THEIR USES | Eisai Co., Ltd. (JP) | 2004-10-13 | — | — | EP | disclosed |
| WO-2003047577-A2 | PHARMACEUTICAL COMPOSITIONS COMPRISING DIHYDROPYRIDINONE COMPOUNDS AND AN IMMUNOREGULATORY OR AN ANTIINFLAMMATORY AGENT AND THEIR USES | EISAI CO LTD (JP) | 2003-06-12 | — | — | WO | disclosed |