Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT2B | Q92831 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | CASP7 | P55210 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | IDO1 | P14902 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL972656 | 0.85 | ALDH1A1 (0.65) | KAT2BMAPTL3MBTL1MAPK1MEN1 | |
| SCHEMBL29504306 | 0.85 | ALDH1A1 (0.65) | KAT2BMAPTL3MBTL1MAPK1MEN1 | |
| SCHEMBL7973853 | 0.82 | KAT2B (0.66) | KAT2BMAPTL3MBTL1MAPK1MEN1 | |
| SCHEMBL162875 | 0.81 | KAT2B (0.60) | KAT2BMAPTL3MBTL1MAPK1MEN1 | |
| SCHEMBL6198859 | 0.81 | KAT2B (0.80) | KAT2BMAPTL3MBTL1MAPK1MEN1 | |
| SCHEMBL29516821 | 0.81 | KAT2B (0.64) | KAT2BMAPTL3MBTL1MAPK1MEN1 | |
| SCHEMBL9781715 | 0.81 | KAT2B (0.64) | KAT2BMAPTL3MBTL1MAPK1MEN1 | |
| SCHEMBL12515298 | 0.81 | KAT2B (0.69) | KAT2BMAPTL3MBTL1MAPK1MEN1 | |
| Bromide SCHEMBL28202540 | 0.80 | KAT2B (0.58) | KAT2BMAPTL3MBTL1MAPK1MEN1 | |
| Hydrochloric Acid SCHEMBL3652036 | 0.80 | KAT2B (0.61) | KAT2BMAPTL3MBTL1MAPK1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015057963-A1 | FGFR4 INHIBITORS | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2015-04-23 | — | — | WO | disclosed |