Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 10/20 | 0.76 |
| ▸ | MAPT | P10636 | 9/20 | 0.76 |
| ▸ | BACE1 | P56817 | 5/20 | 0.76 |
| ▸ | MMP9 | P14780 | 4/20 | 0.76 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.76 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.76 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.76 |
| ▸ | TSHR | P16473 | 2/20 | 0.76 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.76 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.76 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.76 |
| ▸ | MAOA | P21397 | 2/20 | 0.76 |
| ▸ | MAOB | P27338 | 2/20 | 0.76 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.76 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.76 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.76 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.76 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.76 |
| ▸ | STAT3 | P40763 | 2/20 | 0.76 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.76 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Curcumin SCHEMBL1665540 | 1.00 | APP (0.76) | APPMAPTBACE1MMP9NFKB1 | |
| SCHEMBL27994852 | 0.90 | APP (0.80) | APPMAPTBACE1MMP9NFKB1 | |
| SCHEMBL13978651 | 0.88 | PTGES (0.77) | APPMAPTBACE1MMP9NFKB1 | |
| SCHEMBL30393629 | 0.88 | PTGES (0.77) | APPMAPTBACE1MMP9NFKB1 | |
| Curcumin SCHEMBL26626638 | 0.87 | APP (0.94) | APPMAPTBACE1MMP9NFKB1 | |
| Curcumin SCHEMBL28005444 | 0.87 | APP (0.94) | APPMAPTBACE1MMP9NFKB1 | |
| Curcumin SCHEMBL250984 | 0.87 | APP (1.00) | APPMAPTBACE1MMP9NFKB1 | |
| Curcumin SCHEMBL17629819 | 0.87 | APP (1.00) | APPMAPTBACE1MMP9NFKB1 | |
| Curcumin SCHEMBL2804734 | 0.87 | APP (1.00) | APPMAPTBACE1MMP9NFKB1 | |
| Curcumin SCHEMBL8440 | 0.87 | APP (1.00) | APPMAPTBACE1MMP9NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8728453-B2 | Combinatorial polymeric compositions for drug delivery | INNOVOTECH, LLC (US) | 2014-05-20 | — | — | US | claimed |
| US-8513374-B2 | Biocompatible and biodegradable polymers from renewable natural polyphenols | INNOVOTECH, LLC | 2013-08-20 | — | — | US | claimed |
| US-20120220749-A1 | COMBINATIORIAL POLYMERIC COMPOSITIONS FOR DRUG DELIVERY | INNOVOTECH, LLC | 2012-08-30 | — | — | US | claimed |
| US-20120184682-A1 | BIOCOMPATIBLE AND BIODEGRADABLE POLYMERS FROM RENEWABLE NATURAL POLYPHENOLS | INNOVOTECH, LLC (US) | 2012-07-19 | — | — | US | claimed |
| WO-2011041487-A1 | BIOCOMPATIBLE AND BIODEGRADABLE POLYMERS FROM RENEWABLE NATURAL POLYPHENOLS | INNOVOTECH, LLC (US) | 2011-04-07 | — | — | WO | claimed |
| US-20240336575-A1 | POLYTHIOL COMPOUNDS AND PROCESS FOR PREPARATION THEREOF | HENKEL AG & CO KGAA (DE) | 2024-10-10 | — | — | US | disclosed |
| US-20240336740-A1 | POLYTHIOL COMPOUNDS AND PROCESS FOR PREPARATION THEREOF | HENKEL AG & CO KGAA (DE) | 2024-10-10 | — | — | US | disclosed |
| US-20240327341-A1 | POLYTHIOL COMPOUNDS AND PROCESS FOR PREPARATION THEREOF | HENKEL AG & CO KGAA (DE) | 2024-10-03 | — | — | US | disclosed |
| CN-118401498-A | Polythiol compound and process for producing the same | 汉高股份有限及两合公司 | 2024-07-26 | — | — | CN | disclosed |
| CN-118401566-A | Polythiol compound and process for producing the same | 汉高股份有限及两合公司 | 2024-07-26 | — | — | CN | disclosed |
| EP-4198028-B1 | POLYTHIOL COMPOUNDS AND PROCESS FOR PREPARATION THEREOF | HENKEL AG & CO KGAA (DE) | 2024-07-17 | — | — | EP | disclosed |
| EP-4198062-B1 | POLYTHIOL COMPOUNDS AND PROCESS FOR PREPARATION THEREOF | HENKEL AG & CO KGAA (DE) | 2024-07-17 | — | — | EP | disclosed |
| WO-2023110270-A1 | POLYTHIOL COMPOUNDS AND PROCESS FOR PREPARATION THEREOF | HENKEL AG & CO. KGAA (DE) | 2023-06-22 | — | — | WO | disclosed |
| WO-2023110273-A1 | POLYTHIOL COMPOUNDS AND PROCESS FOR PREPARATION THEREOF | HENKEL AG & CO. KGAA (DE) | 2023-06-22 | — | — | WO | disclosed |
| EP-4198028-A1 | POLYTHIOL COMPOUNDS AND PROCESS FOR PREPARATION THEREOF | Henkel AG & Co. KGaA (DE) | 2023-06-21 | — | — | EP | disclosed |
| EP-4198062-A1 | POLYTHIOL COMPOUNDS AND PROCESS FOR PREPARATION THEREOF | Henkel AG & Co. KGaA (DE) | 2023-06-21 | — | — | EP | disclosed |
| EP-4198018-A1 | POLYTHIOL COMPOUNDS AND PROCESS FOR PREPARATION THEREOF | Henkel AG & Co. KGaA (DE) | 2023-06-21 | — | — | EP | disclosed |
| US-8513374-B2 | Biocompatible and biodegradable polymers from renewable natural polyphenols | INNOVOTECH, LLC | 2013-08-20 | — | — | US | disclosed |
| US-20120184682-A1 | BIOCOMPATIBLE AND BIODEGRADABLE POLYMERS FROM RENEWABLE NATURAL POLYPHENOLS | INNOVOTECH, LLC (US) | 2012-07-19 | — | — | US | disclosed |
| WO-2011041487-A1 | BIOCOMPATIBLE AND BIODEGRADABLE POLYMERS FROM RENEWABLE NATURAL POLYPHENOLS | INNOVOTECH, LLC (US) | 2011-04-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240336575-A1 | POLYTHIOL COMPOUNDS AND PROCESS FOR PREPARATION THEREOF | VRK2, VRK1, PTMS | APP 805/4885MAPT 4083/4885BACE1 3037/4885 |
| US-20240327341-A1 | POLYTHIOL COMPOUNDS AND PROCESS FOR PREPARATION THEREOF | VCL, C9, VRK1 | APP 1769/4885MAPT 3991/4885BACE1 3316/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.