Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 5/20 | 0.45 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.45 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.45 |
| ▸ | ANPEP | P15144 | 5/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.41 |
| ▸ | FAAH | O00519 | 2/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16267050 | 0.81 | GABRA1 (0.43) | DPP4NR1H2NR1H3ANPEPGABRA1 | |
| SCHEMBL29042594 | 0.79 | GABRA1 (0.41) | DPP4NR1H2NR1H3ANPEPGABRA1 | |
| SCHEMBL22320712 | 0.79 | GABRA1 (0.41) | DPP4NR1H2NR1H3ANPEPGABRA1 | |
| SCHEMBL2243365 | 0.79 | GABRA1 (0.41) | DPP4NR1H2NR1H3ANPEPGABRA1 | |
| SCHEMBL1821813 | 0.79 | GABRA1 (0.41) | DPP4NR1H2NR1H3ANPEPGABRA1 | |
| SCHEMBL28502131 | 0.79 | GABRA1 (0.41) | DPP4NR1H2NR1H3ANPEPGABRA1 | |
| SCHEMBL29445003 | 0.79 | GABRA1 (0.41) | DPP4NR1H2NR1H3ANPEPGABRA1 | |
| SCHEMBL21723903 | 0.79 | GABRA1 (0.41) | DPP4NR1H2NR1H3ANPEPGABRA1 | |
| SCHEMBL30976692 | 0.79 | GABRA1 (0.41) | DPP4NR1H2NR1H3ANPEPGABRA1 | |
| Hydrochloric Acid SCHEMBL25179558 | 0.78 | DPP4 (0.40) | DPP4NR1H2NR1H3ANPEPGABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118834188-A | New process for preparing simvastatin | 江苏阿尔法药业股份有限公司 | 2024-10-25 | — | — | CN | claimed |
| CN-115232086-B | Preparation method of 4-benzyl-2 (3H) -oxazolone | 扬州市普林斯医药科技有限公司 | 2024-05-03 | — | — | CN | claimed |
| CN-115010677-B | Preparation method of 4-phenyl-2 (3H) -oxazolone | 扬州市普林斯医药科技有限公司 | 2024-05-03 | — | — | CN | claimed |
| CN-118834188-A | New process for preparing simvastatin | 江苏阿尔法药业股份有限公司 | 2024-10-25 | — | — | CN | disclosed |
| CN-118841369-A | Method for metallization of ultra-high depth-to-width ratio through silicon vias of three-dimensional integrated circuit | 厦门大学 | 2024-10-25 | — | — | CN | disclosed |
| CN-115232086-B | Preparation method of 4-benzyl-2 (3H) -oxazolone | 扬州市普林斯医药科技有限公司 | 2024-05-03 | — | — | CN | disclosed |
| CN-115010677-B | Preparation method of 4-phenyl-2 (3H) -oxazolone | 扬州市普林斯医药科技有限公司 | 2024-05-03 | — | — | CN | disclosed |
| CN-113402511-B | Preparation method of topramezone | 西安交通大学 | 2023-04-07 | — | — | CN | disclosed |
| US-10759764-B2 | Fluorination of organic compounds | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2020-09-01 | — | — | US | disclosed |
| WO-2017158275-A1 | METHOD FOR PREPARING ALKYLAMINES | COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) | 2017-09-21 | — | — | WO | disclosed |
| US-20160272593-A1 | FLUORINATION OF ORGANIC COMPOUNDS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2016-09-22 | — | — | US | disclosed |
| US-20160272593-A1 | FLUORINATION OF ORGANIC COMPOUNDS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2016-09-22 | — | — | US | disclosed |
| WO-2015058047-A2 | FLUORINATION OF ORGANIC COMPOUNDS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2015-04-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160272593-A1 | FLUORINATION OF ORGANIC COMPOUNDS | FLI1, SLCO2B1, SLCO1B3 | DPP4 2338/4885NR1H2 1942/4885NR1H3 1281/4885 |
| US-10759764-B2 | Fluorination of organic compounds | FLI1, SLCO2B1, SLCO1B3 | DPP4 2338/4885NR1H2 1942/4885NR1H3 1281/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.