SCHEMBL21723903

SCHEMBL21723903

CC(C)c1cccc(C(C)C)c1-n1ccn(-c2c(C(C)C)cccc2C(C)C)c1=[Au]

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 3/20 0.41
GABRG2 P18507 2/20 0.41
GABRB3 P28472 2/20 0.41
GABRB2 P47870 2/20 0.41
TSHR P16473 2/20 0.41
FAAH O00519 2/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
LMNA P02545 1/20 0.41
CYP1A2 P05177 1/20 0.41
CYP3A4 P08684 1/20 0.41
HPGD P15428 1/20 0.41
GABRB1 P18505 1/20 0.41
PTGS1 P23219 1/20 0.41
SLC6A2 P23975 1/20 0.41
HTR2C P28335 1/20 0.41
GABRA5 P31644 1/20 0.41
GABRA3 P34903 1/20 0.41
HTR2B P41595 1/20 0.41
GABRA2 P47869 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL2798765 0.98 GABRA1 (0.40) GABRA1GABRG2GABRB3GABRB2TSHR
SCHEMBL19810044 0.93 DPP4 (0.39) GABRA1GABRG2GABRB3GABRB2TSHR
SCHEMBL19514082 0.93 DPP4 (0.39) GABRA1GABRG2GABRB3GABRB2TSHR
SCHEMBL16267050 0.81 GABRA1 (0.43) GABRA1GABRG2GABRB3GABRB2TSHR
SCHEMBL4216299 0.80 DPP4 (0.41) GABRA1GABRG2GABRB3GABRB2TSHR
SCHEMBL16655509 0.79 DPP4 (0.45) GABRA1GABRG2GABRB3GABRB2TSHR
SCHEMBL29445003 0.79 GABRA1 (0.41) GABRA1GABRG2GABRB3GABRB2TSHR
SCHEMBL22320712 0.79 GABRA1 (0.41) GABRA1GABRG2GABRB3GABRB2TSHR
SCHEMBL1821813 0.79 GABRA1 (0.41) GABRA1GABRG2GABRB3GABRB2TSHR
SCHEMBL29042594 0.79 GABRA1 (0.41) GABRA1GABRG2GABRB3GABRB2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118103021-A Esters of 5-methylhex-2-enol and use thereof as fragrance chemicals 巴斯夫欧洲公司 2024-05-28 CN claimed
CN-116390905-A Intermolecular reaction of acetylene with 2-alkylfuran in the presence of gold (I) complex to form para-alkylphenol 帝斯曼知识产权资产管理有限公司 2023-07-04 CN claimed
CN-115785104-A Method for synthesizing spiro [ indoline-3, 3' -pyrrolidine ] derivative catalyzed by monovalent gold 沈阳药科大学 2023-03-14 CN claimed
CN-115785087-A Method for synthesizing 1H-pyrido [4,3-b ] indole skeleton compound catalyzed by monovalent gold 沈阳药科大学 2023-03-14 CN claimed
CN-115772171-A Method for synthesizing spiro [ indoline-3, 3' -piperidine ] skeleton under catalysis of monovalent gold 沈阳药科大学 2023-03-10 CN claimed
WO-2020036243-A1 METHOD FOR SYNTHESIZING THIENO[3,2-B]PYRIDINE-5(4H)-ONE DERIVATIVE COMPOUND, USING GOLD CATALYST, AND USE THEREFOR 한국해양과학기술원 2020-02-20 WO claimed
EP-4396187-A1 NAPHTHYRIDINE COMPOUNDS AS INHIBITORS OF KRAS Incyte Corporation (US) 2024-07-10 EP disclosed
CN-118103021-A Esters of 5-methylhex-2-enol and use thereof as fragrance chemicals 巴斯夫欧洲公司 2024-05-28 CN disclosed
CN-116390905-A Intermolecular reaction of acetylene with 2-alkylfuran in the presence of gold (I) complex to form para-alkylphenol 帝斯曼知识产权资产管理有限公司 2023-07-04 CN disclosed
CN-115785104-A Method for synthesizing spiro [ indoline-3, 3' -pyrrolidine ] derivative catalyzed by monovalent gold 沈阳药科大学 2023-03-14 CN disclosed
CN-115785087-A Method for synthesizing 1H-pyrido [4,3-b ] indole skeleton compound catalyzed by monovalent gold 沈阳药科大学 2023-03-14 CN disclosed
WO-2023034290-A1 NAPHTHYRIDINE COMPOUNDS AS INHIBITORS OF KRAS INCYTE CORPORATION (US) 2023-03-09 WO disclosed
EP-4127162-A1 MODIFIED DNA-ENCODED CHEMICAL LIBRARY AND METHODS RELATED THERETO Technische Universität Dortmund (DE) 2023-02-08 EP disclosed
CN-113498342-A Compounds involved in synergistic binding and uses thereof 锐新医药公司 2021-10-12 CN disclosed
CN-108929215-B Synthesis method of cis-alpha-halogenated alpha, beta-unsaturated ketone compound 浙江工业大学 2021-07-27 CN disclosed
CN-108863751-B Synthetic method of Z-type halogenated chalcone compound 浙江工业大学 2021-07-27 CN disclosed
WO-2020036243-A1 METHOD FOR SYNTHESIZING THIENO[3,2-B]PYRIDINE-5(4H)-ONE DERIVATIVE COMPOUND, USING GOLD CATALYST, AND USE THEREFOR 한국해양과학기술원 2020-02-20 WO disclosed
CN-108929215-A A kind of synthetic method of the halogenated alpha, beta unsaturated ketone class compound of cis- α 浙江工业大学 2018-12-04 CN disclosed
CN-108863751-A A kind of synthetic method of the halogenated chalcone compounds of Z formula 浙江工业大学 2018-11-23 CN disclosed