Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 3/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | FAAH | O00519 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16267050 | 0.81 | GABRA1 (0.43) | GABRA1GABRG2GABRB3GABRB2TSHR | |
| SCHEMBL29042594 | 0.79 | GABRA1 (0.41) | GABRA1GABRG2GABRB3GABRB2TSHR | |
| SCHEMBL21723903 | 0.79 | GABRA1 (0.41) | GABRA1GABRG2GABRB3GABRB2TSHR | |
| SCHEMBL2243365 | 0.79 | GABRA1 (0.41) | GABRA1GABRG2GABRB3GABRB2TSHR | |
| SCHEMBL1821813 | 0.79 | GABRA1 (0.41) | GABRA1GABRG2GABRB3GABRB2TSHR | |
| SCHEMBL28502131 | 0.79 | GABRA1 (0.41) | GABRA1GABRG2GABRB3GABRB2TSHR | |
| SCHEMBL16655509 | 0.79 | DPP4 (0.45) | GABRA1GABRG2GABRB3GABRB2TSHR | |
| SCHEMBL22320712 | 0.79 | GABRA1 (0.41) | GABRA1GABRG2GABRB3GABRB2TSHR | |
| SCHEMBL30976692 | 0.79 | GABRA1 (0.41) | GABRA1GABRG2GABRB3GABRB2TSHR | |
| Hydrochloric Acid SCHEMBL25179558 | 0.78 | DPP4 (0.40) | GABRA1GABRG2GABRB3GABRB2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4161904-A1 | INTERMEDIATES AND PROCESSES FOR THE PREPARATION OF TOLVAPTAN AND ITS DERIVATIVES | Cambrex Profarmaco Milano S.r.l. (IT) | 2023-04-12 | — | — | EP | claimed |
| EP-4161904-A1 | INTERMEDIATES AND PROCESSES FOR THE PREPARATION OF TOLVAPTAN AND ITS DERIVATIVES | Cambrex Profarmaco Milano S.r.l. (IT) | 2023-04-12 | — | — | EP | disclosed |
| US-11279696-B2 | Processes for the preparation of 7-{4-[4-(1-benzothiophen-4-yl) piperazin-1-yl]butoxy}quinolin-2(1H)-one | MSN LABORATORIES PRIVATE LIMITED (IN) | 2022-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11279696-B2 | Processes for the preparation of 7-{4-[4-(1-benzothiophen-4-yl) piperazin-1-yl]butoxy}quinolin-2(1H)-one | CYP1B1, CYP4B1, CYP1A1 | GABRA1 664/4885GABRG2 1330/4885GABRB3 1533/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.