Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 7/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.39 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.38 |
| ▸ | GABRP | O00591 | 1/20 | 0.37 |
| ▸ | GABRD | O14764 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.37 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.37 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16655925 | 0.79 | KMT2A (0.39) | SLC6A4SLC6A2SLC6A3KCNH2MEN1 | |
| SCHEMBL8326384 | 0.73 | GBA1 (0.42) | SLC6A4SLC6A2SLC6A3KCNH2MEN1 | |
| SCHEMBL16655739 | 0.73 | SIGMAR1 (0.53) | SLC6A4KMT2AOPRD1TSHROPRM1 | |
| SCHEMBL408318 | 0.71 | KMT2A (0.66) | MEN1CYP2D6KMT2AGABRPGABRD | |
| SCHEMBL27615711 | 0.71 | ELANE (0.47) | SLC6A4SLC6A3MEN1CYP2D6KMT2A | |
| SCHEMBL818792 | 0.70 | GBA1 (0.39) | SLC6A4SLC6A2SLC6A3KCNH2MEN1 | |
| Bromide SCHEMBL10968790 | 0.70 | KMT2A (0.64) | MEN1CYP2D6KMT2AGABRPGABRD | |
| SCHEMBL27654505 | 0.70 | CES2 (0.47) | TSHRPMP22CES2CES1 | |
| SCHEMBL14677357 | 0.70 | CES1 (0.47) | MEN1KMT2ATSHRPMP22CES2 | |
| Hydrochloric Acid SCHEMBL227939 | 0.70 | KMT2A (0.69) | MEN1CYP2D6KMT2AGABRPGABRD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015057963-A1 | FGFR4 INHIBITORS | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2015-04-23 | — | — | WO | disclosed |