SCHEMBL16656146

SCHEMBL16656146

Cc1ccc2c(c1)C1(c3cc(Br)ccc3-2)c2cc(Br)ccc2-c2ccc(Br)cc21

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.42
MAPK1 P28482 1/20 0.41
S100A4 P26447 1/20 0.40
PDK2 Q15119 4/20 0.40
PTPRC P08575 1/20 0.35
AKR1A1 P14550 1/20 0.35
AKR1B1 P15121 1/20 0.35
CA1 P00915 2/20 0.34
CA2 P00918 2/20 0.34
CA4 P22748 2/20 0.34
CA7 P43166 2/20 0.34
CA9 Q16790 2/20 0.34
TDP2 O95551 1/20 0.34
AGTR1 P30556 1/20 0.34
MALT1 Q9UDY8 1/20 0.33
TGM2 P21980 1/20 0.33
CES1 P23141 1/20 0.33
MAOA P21397 1/20 0.33
MAOB P27338 1/20 0.33
LMNA P02545 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23989351 0.91 PDK2 (0.49) ALDH1A1MAPK1S100A4PDK2PTPRC
SCHEMBL14831134 0.91 PDK2 (0.49) ALDH1A1MAPK1S100A4PDK2PTPRC
SCHEMBL19286810 0.87 PDK2 (0.47) ALDH1A1PDK2CA1CA2CA4
SCHEMBL437007 0.87 PDK2 (0.47) ALDH1A1MAPK1S100A4PDK2PTPRC
SCHEMBL29404184 0.87 PDK2 (0.47) ALDH1A1MAPK1S100A4PDK2PTPRC
SCHEMBL13636721 0.87 PDK2 (0.39) ALDH1A1MAPK1S100A4PDK2MAOB
SCHEMBL429929 0.86 ALDH1A1 (0.41) ALDH1A1MAPK1S100A4PDK2PTPRC
SCHEMBL15315869 0.86 ALDH1A1 (0.41) ALDH1A1MAPK1S100A4PDK2PTPRC
SCHEMBL12109715 0.86 PDK2 (0.41) ALDH1A1MAPK1S100A4PDK2PTPRC
SCHEMBL14314032 0.85 ALDH1A1 (0.35) ALDH1A1MAPK1S100A4PDK2AGTR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9406943-B2 Electrocatalysts using porous polymers and method of preparation UCHICAGO ARGONNE, LLC (US) 2016-08-02 US disclosed
WO-2016009231-A1 NANOPARTICLES THE UNIVERSITY OF MANCHESTER (GB) 2016-01-21 WO disclosed
US-20150194681-A1 ELECTROCATALYSTS USING POROUS POLYMERS AND METHOD OF PREPARATION UCHICAGO ARGONNE, LLC (US) 2015-07-09 US disclosed
US-9012344-B2 Electrocatalysts using porous polymers and method of preparation UCHICAGO ARGONNE, LLC (US) 2015-04-21 US disclosed