SCHEMBL429929

SCHEMBL429929

Cc1ccc2c(c1)C(C)(C)c1cc(Br)ccc1-2

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.41
MAPK1 P28482 2/20 0.40
S100A4 P26447 1/20 0.39
PDK2 Q15119 2/20 0.39
MALT1 Q9UDY8 1/20 0.36
MAPT P10636 3/20 0.35
HTT P42858 2/20 0.35
MEN1 O00255 1/20 0.35
LMNA P02545 1/20 0.35
THRB P10828 1/20 0.35
RECQL P46063 1/20 0.35
KMT2A Q03164 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
PGR P06401 2/20 0.35
PTPRC P08575 1/20 0.34
NPC1 O15118 1/20 0.34
AKR1A1 P14550 1/20 0.34
AKR1B1 P15121 1/20 0.34
CA1 P00915 2/20 0.33
CA2 P00918 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18615369 0.96 ALDH1A1 (0.38) ALDH1A1MAPK1S100A4PDK2MALT1
SCHEMBL12439574 0.96 ALDH1A1 (0.38) ALDH1A1MAPK1S100A4PDK2MALT1
SCHEMBL29403081 0.89 PDK2 (0.44) S100A4PDK2MALT1PGRPTPRC
SCHEMBL204806 0.89 PDK2 (0.44) S100A4PDK2MALT1PGRPTPRC
SCHEMBL29587737 0.89 PDK2 (0.44) S100A4PDK2MALT1PGRPTPRC
SCHEMBL15315869 0.88 ALDH1A1 (0.41) ALDH1A1MAPK1S100A4PDK2MALT1
SCHEMBL4368315 0.87 PDK2 (0.46) ALDH1A1MAPK1PDK2MAPTHTT
SCHEMBL16656146 0.86 ALDH1A1 (0.42) ALDH1A1MAPK1S100A4PDK2MALT1
SCHEMBL22884256 0.85 PDK2 (0.41) ALDH1A1MAPK1PDK2MAPTHTT
SCHEMBL13911507 0.85 PDK2 (0.44) ALDH1A1PDK2MAPTMEN1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240237529-A1 NOVEL COMPOUND, AND PHOTOELECTRIC DEVICE, IMAGE SENSOR, AND ELECTRONIC DEVICE INCLUDING SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2024-07-11 US disclosed
US-11784305-B2 Negative electrode including silicon nanoparticles having a carbon coating thereon GM Global Technology Operations LLC (US) 2023-10-10 US disclosed
US-20230212334-A1 POLYMER, ELECTROLUMINESCENCE MATERIAL, ELECTROLUMINESCENCE DEVICE, AND ELECTRONIC DEVICE SAMSUNG ELECTRONICS CO LTD (KR) 2023-07-06 US disclosed
US-20230194165-A1 RADIOFREQUENCY HEATING OF WOOD USING A THREE-ELECTRODE SYSTEM HAVING A WINGED CENTRAL ELECTRODE RF KILN TECH LIMITED (CA) 2023-06-22 US disclosed
US-11666637-B2 Insulin-loaded metal-organic frameworks NORTHWESTERN UNIVERSITY (US) 2023-06-06 US disclosed
WO-2020241730-A1 ARYLAMINE COMPOUND AND USE THEREOF 日産化学株式会社 2020-12-03 WO disclosed
EP-3674343-A1 POLYMER COMPOUND AND LIGHT-EMITTING ELEMENT USING SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2020-07-01 EP disclosed
EP-2881446-B1 Organic compound and organic light emitting diode using the same LG DISPLAY CO LTD (KR) 2019-01-09 EP disclosed
WO-2018113786-A1 CROSS-LINKABLE POLYMER BASED ON DIELS-ALDER REACTION AND USE THEREOF IN ORGANIC ELECTRONIC DEVICE 广州华睿光电材料有限公司 2018-06-28 WO disclosed
US-20180123124-A1 NEGATIVE ELECTRODE INCLUDING SILICON NANOPARTICLES HAVING A CARBON COATING THEREON GM Global Technology Operations LLC 2018-05-03 US disclosed
US-20110177312-A1 LAMINATED STRUCTURE, METHOD FOR PRODUCING SAME, AND ELECTRONIC ELEMENT COMPRISING SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-07-21 US disclosed
US-20100187511-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2010-07-29 US disclosed
US-20100187511-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2010-07-29 US disclosed
US-20100069603-A1 METHOD FOR PRODUCING STRUCTURE WHEREIN AROMATIC POLYMER IS BONDED TO BASE, STRUCTURE HAVING AROMATIC POLYMER CHAIN BONDED TO CONDUCTIVE BASE, AND ELECTRONIC DEVICE COMPRISING THE STRUCTURE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-03-18 US disclosed
US-20100069603-A1 METHOD FOR PRODUCING STRUCTURE WHEREIN AROMATIC POLYMER IS BONDED TO BASE, STRUCTURE HAVING AROMATIC POLYMER CHAIN BONDED TO CONDUCTIVE BASE, AND ELECTRONIC DEVICE COMPRISING THE STRUCTURE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-03-18 US disclosed
US-20100051914-A1 Silicon-containing compound and organic electroluminescent device employing the same SAMSUNG MOBILE DISPLAY CO., LTD. (KR) 2010-03-04 US disclosed
EP-2159217-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME Idemitsu Kosan Co., Ltd. (JP) 2010-03-03 EP disclosed
US-20090091252-A1 BINAPHTHYL COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT USING THE SAME CANON KABUSHIKI KAISHA (JP) 2009-04-09 US disclosed
US-20090091252-A1 BINAPHTHYL COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT USING THE SAME CANON KABUSHIKI KAISHA (JP) 2009-04-09 US disclosed
EP-2045231-A1 Binaphthyl compound and organic light emitting element using the same Canon Kabushiki Kaisha (JP) 2009-04-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110177312-A1 LAMINATED STRUCTURE, METHOD FOR PRODUCING SAME, AND ELECTRONIC ELEMENT COMPRISING SAME EPCAM, ITGA1, ITGB1 ALDH1A1 618/4885MAPK1 1380/4885S100A4 223/4885
US-11666637-B2 Insulin-loaded metal-organic frameworks IAPP, IGFBP4, IGFBP1 ALDH1A1 4660/4885MAPK1 4202/4885S100A4 2358/4885
US-20090091252-A1 BINAPHTHYL COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT USING THE SAME ALPL, MT-ND4L, LAGE3 ALDH1A1 476/4885MAPK1 4630/4885S100A4 1839/4885
US-20240237529-A1 NOVEL COMPOUND, AND PHOTOELECTRIC DEVICE, IMAGE SENSOR, AND ELECTRONIC DEVICE INCLUDING SAME CRY1, NCS1, CYP4X1 ALDH1A1 24/4885MAPK1 9/4885S100A4 1454/4885
US-20100051914-A1 Silicon-containing compound and organic electroluminescent device employing the same SLCO4C1, SLC7A5, SLCO2B1 ALDH1A1 2554/4885MAPK1 557/4885S100A4 4037/4885
US-20100187511-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME TYR, DDC, OCIAD2 ALDH1A1 428/4885MAPK1 752/4885S100A4 1722/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.