Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | BCL2 | P10415 | 3/20 | 0.40 |
| ▸ | BCL2L2 | Q92843 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16656338 | 0.86 | ALDH1A1 (0.49) | TP53BCL2BCL2L2ALDH1A1MCL1 | |
| SCHEMBL21449404 | 0.81 | BCL2 (0.45) | TP53BCL2BCL2L2ALDH1A1MCL1 | |
| SCHEMBL478909 | 0.76 | ALDH1A1 (0.64) | TP53MAPTBCL2BCL2L2ALDH1A1 | |
| SCHEMBL11616001 | 0.76 | ALDH1A1 (0.64) | TP53MAPTBCL2BCL2L2ALDH1A1 | |
| SCHEMBL4609039 | 0.76 | ALDH1A1 (0.64) | TP53MAPTBCL2BCL2L2ALDH1A1 | |
| SCHEMBL25583427 | 0.76 | KDM4E (0.58) | TP53MAPTBCL2BCL2L2ALDH1A1 | |
| SCHEMBL21851967 | 0.71 | ALDH1A1 (0.50) | TP53BCL2BCL2L2ALDH1A1GAA | |
| SCHEMBL24705626 | 0.70 | MCL1 (0.45) | TP53MAPTALDH1A1MCL1GAA | |
| SCHEMBL21852156 | 0.69 | ALDH1A1 (0.66) | TP53BCL2BCL2L2ALDH1A1MCL1 | |
| SCHEMBL16601635 | 0.69 | ALDH1A1 (0.43) | MAPTALDH1A1GAAKDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9012112-B2 | Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus | CANON KABUSHIKI KAISHA (JP) | 2015-04-21 | — | — | US | disclosed |