Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.64 |
| ▸ | GAA | P10253 | 2/20 | 0.64 |
| ▸ | POLB | P06746 | 4/20 | 0.62 |
| ▸ | TP53 | P04637 | 2/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | GLA | P06280 | 1/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.62 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.62 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.62 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.62 |
| ▸ | APEX1 | P27695 | 1/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.56 |
| ▸ | BCL2 | P10415 | 2/20 | 0.54 |
| ▸ | BCL2L2 | Q92843 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4609039 | 1.00 | ALDH1A1 (0.64) | ALDH1A1GAAPOLBTP53KDM4E | |
| SCHEMBL11616001 | 1.00 | ALDH1A1 (0.64) | ALDH1A1GAAPOLBTP53KDM4E | |
| SCHEMBL16656338 | 0.88 | ALDH1A1 (0.49) | ALDH1A1GAAPOLBTP53KDM4E | |
| SCHEMBL27883350 | 0.87 | ALDH1A1 (0.59) | ALDH1A1GAAPOLBTP53KDM4E | |
| SCHEMBL25583427 | 0.86 | KDM4E (0.58) | ALDH1A1GAAPOLBTP53KDM4E | |
| SCHEMBL9449206 | 0.86 | LMNA (0.65) | ALDH1A1GAAPOLBTP53KDM4E | |
| SCHEMBL5422287 | 0.85 | ALDH1A1 (0.60) | ALDH1A1GAAPOLBTP53KDM4E | |
| SCHEMBL12291598 | 0.85 | ALDH1A1 (0.60) | ALDH1A1GAAPOLBTP53KDM4E | |
| SCHEMBL6689063 | 0.85 | ALDH1A1 (0.63) | ALDH1A1GAAPOLBTP53KDM4E | |
| SCHEMBL19359464 | 0.85 | ALDH1A1 (0.63) | ALDH1A1GAAPOLBTP53KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7723425-B2 | Pigment compositions with modified ATRP copolymer dispersants | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2010-05-25 | — | — | US | claimed |
| EP-1477486-A2 | Imides as inhibitors of TNF alpha | CELGENE CORPORATION (US) | 2004-11-17 | — | — | EP | claimed |
| US-11998901-B2 | Metal complex, method for producing same, and method for producing gamma-lactam compound using same | INSTITUTE FOR BASIC SCIENCE (KR) | 2024-06-04 | — | — | US | disclosed |
| US-20230312577-A1 | DUAL KINASE-BROMODOMAIN INHIBITORS | MONASH UNIVERSITY (AU) | 2023-10-05 | — | — | US | disclosed |
| CN-111566116-B | Novel metal complex, process for producing the same, and process for producing gamma-lactam compound using the same | 基础科学研究院 | 2023-06-09 | — | — | CN | disclosed |
| US-20220168717-A1 | NOVEL METAL COMPLEX, METHOD FOR PRODUCING SAME, AND METHOD FOR PRODUCING GAMMA-LACTAM COMPOUND USING SAME | INSTITUTE FOR BASIC SCIENCE (KR) | 2022-06-02 | — | — | US | disclosed |
| US-11344872-B2 | Metal complex, method for producing same, and method for producing gamma-lactam compound using same | INSTITUTE FOR BASIC SCIENCE (KR) | 2022-05-31 | — | — | US | disclosed |
| US-20200330969-A1 | NOVEL METAL COMPLEX, METHOD FOR PRODUCING SAME, AND METHOD FOR PRODUCING GAMMA-LACTAM COMPOUND USING SAME | KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2020-10-22 | — | — | US | disclosed |
| CN-111566116-A | Novel metal complex, method for producing same, and method for producing gamma-lactam compound using same | 基础科学研究院 | 2020-08-21 | — | — | CN | disclosed |
| US-10138236-B2 | Factor xia-inhibiting pyridobenzazepine and pyridobenzazocine derivatives | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2018-11-27 | — | — | US | disclosed |
| EP-3197891-B1 | FACTOR XIA-INHIBITING PYRIDOBENZAZEPINE AND PYRIDOBENZAZOCINE DERIVATIVES | Bayer Pharma AG (DE) | 2018-11-21 | — | — | EP | disclosed |
| US-5605914-A | INHIBITORS OF TUMOR NECROSIS FACTOR | CELGENE CORPORATION (US) | 1997-02-25 | — | — | US | disclosed |
| EP-0706521-A1 | NOVEL IMIDES | CELGENE CORPORATION (US) | 1996-04-17 | — | — | EP | disclosed |
| US-5463063-A | Preparation of thalidomide; inhibitor of tumor necrosis factor | CELGENE CORPORATION (US) | 1995-10-31 | — | — | US | disclosed |
| WO-1995001348-A2 | IMIDES AS INHIBITORS OF TNP ALPHA | CELGENE CORPORATION (US) | 1995-01-12 | — | — | WO | disclosed |
| US-5250546-A | Administering as therapy for spastic paralysis; glutamic acid blocking agent; agricultural chemicals | NIPPON CHEMIPHAR CO., LTD. (JP) | 1993-10-05 | — | — | US | disclosed |
| EP-0177245-B1 | AMINO-ALCOHOL DERIVATIVES AND PROCESSES FOR THEIR PREPARATION | NIPPON CHEMIPHAR CO., LTD. (JP) | 1991-04-10 | — | — | EP | disclosed |
| US-4644063-A | MUSCLE RELAXANTS; AGRICULTURE | NIPPON CHEMIPHAR CO., LTD. (JP) | 1987-02-17 | — | — | US | disclosed |
| EP-0208666-A1 | Improvements to explosive charges | Nobel Kemi AB (SE) | 1987-01-14 | — | — | EP | disclosed |
| EP-0177245-A2 | Amino-alcohol derivatives and processes for their preparation | NIPPON CHEMIPHAR CO., LTD. (JP) | 1986-04-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10138236-B2 | Factor xia-inhibiting pyridobenzazepine and pyridobenzazocine derivatives | F13B, TFPI, TFPI2 | ALDH1A1 3966/4885GAA 2228/4885POLB 3568/4885 |
| US-20220168717-A1 | NOVEL METAL COMPLEX, METHOD FOR PRODUCING SAME, AND METHOD FOR PRODUCING GAMMA-LACTAM COMPOUND USING SAME | COASY, NOTUM, MRPL21 | ALDH1A1 2634/4885GAA 132/4885POLB 1168/4885 |
| US-11344872-B2 | Metal complex, method for producing same, and method for producing gamma-lactam compound using same | COASY, NOTUM, MRPL21 | ALDH1A1 2316/4885GAA 105/4885POLB 1090/4885 |
| US-11998901-B2 | Metal complex, method for producing same, and method for producing gamma-lactam compound using same | COASY, NOTUM, MRPL21 | ALDH1A1 2316/4885GAA 105/4885POLB 1090/4885 |
| US-20230312577-A1 | DUAL KINASE-BROMODOMAIN INHIBITORS | MAP2K2, BRPF3, BRDT | ALDH1A1 4173/4885GAA 3101/4885POLB 1099/4885 |
| US-20200330969-A1 | NOVEL METAL COMPLEX, METHOD FOR PRODUCING SAME, AND METHOD FOR PRODUCING GAMMA-LACTAM COMPOUND USING SAME | COASY, NOTUM, MRPL21 | ALDH1A1 2634/4885GAA 132/4885POLB 1168/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.