SCHEMBL16656338

SCHEMBL16656338

CC(C)CC(C(=O)O)N1C(=O)c2ccc3c4c(ccc(c24)C1=O)C(=O)N(C(CC(C)C)C(=O)O)C3=O

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.49
BCL2 P10415 3/20 0.49
BCL2L2 Q92843 3/20 0.49
GAA P10253 2/20 0.49
MCL1 Q07820 3/20 0.48
MAPK1 P28482 2/20 0.47
KDM4E B2RXH2 1/20 0.47
TP53 P04637 1/20 0.47
GLA P06280 1/20 0.47
POLB P06746 1/20 0.47
CYP3A4 P08684 1/20 0.47
CYP2D6 P10635 1/20 0.47
HPGD P15428 1/20 0.47
ALOX12 P18054 1/20 0.47
NFKB1 P19838 1/20 0.47
APEX1 P27695 1/20 0.47
HSD17B10 Q99714 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.46
MEN1 O00255 1/20 0.45
KMT2A Q03164 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21449404 0.94 BCL2 (0.45) ALDH1A1BCL2BCL2L2GAAMCL1
SCHEMBL11616001 0.88 ALDH1A1 (0.64) ALDH1A1BCL2BCL2L2GAAMAPK1
SCHEMBL478909 0.88 ALDH1A1 (0.64) ALDH1A1BCL2BCL2L2GAAMAPK1
SCHEMBL4609039 0.88 ALDH1A1 (0.64) ALDH1A1BCL2BCL2L2GAAMAPK1
SCHEMBL25583427 0.88 KDM4E (0.58) ALDH1A1BCL2BCL2L2GAAMAPK1
SCHEMBL16656200 0.86 TP53 (0.41) ALDH1A1BCL2BCL2L2GAAMCL1
SCHEMBL21851967 0.83 ALDH1A1 (0.50) ALDH1A1BCL2BCL2L2GAAMAPK1
SCHEMBL21852156 0.81 ALDH1A1 (0.66) ALDH1A1BCL2BCL2L2GAAMCL1
SCHEMBL6795134 0.80 SMN1; SMN2 (0.49) ALDH1A1BCL2BCL2L2GAAMCL1
SCHEMBL31259788 0.79 ALDH1A1 (0.47) ALDH1A1BCL2BCL2L2GAAMCL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11061341-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2021-07-13 US disclosed
US-10656542-B2 Electrophotographic photosensitive member, process cartridge, electrophotographic apparatus, and method for producing electrophotographic photosensitive member CANON KABUSHIKI KAISHA (JP) 2020-05-19 US disclosed
US-20200041918-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2020-02-06 US disclosed
US-20190310561-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, ELECTROPHOTOGRAPHIC APPARATUS, AND METHOD FOR PRODUCING ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER CANON KABUSHIKI KAISHA (JP) 2019-10-10 US disclosed
US-10372050-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2019-08-06 US disclosed
US-9012112-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2015-04-21 US disclosed