Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 2/20 | 0.35 |
| ▸ | TOP2A | P11388 | 1/20 | 0.34 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.34 |
| ▸ | NOS3 | P29474 | 2/20 | 0.31 |
| ▸ | NOS1 | P29475 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16601718 | 1.00 | LRRK2 (0.39) | LRRK2ALDH1A1KDRTOP2ATOP2B | |
| SCHEMBL16601743 | 0.67 | MEN1 (0.49) | LRRK2ALDH1A1KDRNOS3NOS1 | |
| SCHEMBL8416365 | 0.66 | PDCD1 (0.39) | ALDH1A1KMT2A | |
| SCHEMBL9153685 | 0.63 | GABRA1 (0.48) | ALDH1A1CA1CA2 | |
| SCHEMBL11996571 | 0.62 | TSHR (0.44) | CA12CA1CA2CA9 | |
| SCHEMBL15687492 | 0.61 | NOTUM (0.34) | ALDH1A1 | |
| SCHEMBL7970456 | 0.60 | LRRK2 (0.44) | LRRK2ALDH1A1KDRTOP2ATOP2B | |
| SCHEMBL9220799 | 0.59 | POLB (0.51) | ALDH1A1NOS3NOS1CA12CA1 | |
| SCHEMBL12111786 | 0.59 | MEN1 (0.48) | ALDH1A1MEN1KMT2A | |
| SCHEMBL18134597 | 0.58 | ALDH1A1 (1.00) | LRRK2ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9012112-B2 | Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus | CANON KABUSHIKI KAISHA (JP) | 2015-04-21 | — | — | US | disclosed |
| US-9012112-B2 | Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus | CANON KABUSHIKI KAISHA (JP) | 2015-04-21 | — | — | US | disclosed |