Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.32 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.32 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.32 |
| ▸ | CA12 | O43570 | 2/20 | 0.31 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | CA4 | P22748 | 2/20 | 0.31 |
| ▸ | CA9 | Q16790 | 2/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.31 |
| ▸ | VHL | P40337 | 1/20 | 0.31 |
| ▸ | ELOC | Q15369 | 1/20 | 0.31 |
| ▸ | ELOB | Q15370 | 1/20 | 0.31 |
| ▸ | LTA4H | P09960 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL516512 | 0.87 | TSHR (0.43) | POLBALDH1A1TDP1TSHRPRSS1 | |
| SCHEMBL1478591 | 0.82 | HDAC8 (0.43) | ALDH1A1TDP1HDAC8CA12CA1 | |
| SCHEMBL308282 | 0.82 | TSHR (0.48) | ALDH1A1TDP1TSHRMEN1KMT2A | |
| SCHEMBL12694295 | 0.80 | PYCR1 (0.40) | POLBALDH1A1TDP1TSHRKMT2A | |
| SCHEMBL309287 | 0.76 | MKNK1 (0.45) | TSHRMEN1KMT2APRSS1PRSS2 | |
| SCHEMBL13599813 | 0.76 | MKNK1 (0.45) | TSHRMEN1KMT2APRSS1PRSS2 | |
| SCHEMBL22941869 | 0.76 | MKNK1 (0.45) | TSHRMEN1KMT2APRSS1PRSS2 | |
| SCHEMBL9891695 | 0.76 | TSHR (0.48) | ALDH1A1TDP1TSHRMEN1KMT2A | |
| SCHEMBL13201579 | 0.76 | CYP2A6 (0.42) | POLBALDH1A1TDP1TSHRHDAC8 | |
| SCHEMBL2433973 | 0.74 | ALDH1A1 (0.50) | ALDH1A1TDP1MEN1KMT2AHDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9012773-B2 | Thiazole-based compound and uses thereof | NEC CORPORATION (JP) | 2015-04-21 | — | — | US | disclosed |