Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.38 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.38 |
| ▸ | VHL | P40337 | 1/20 | 0.37 |
| ▸ | ELOC | Q15369 | 1/20 | 0.37 |
| ▸ | ELOB | Q15370 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL308282 | 0.92 | TSHR (0.48) | TSHRALDH1A1CYP3A4TDP1MAPK1 | |
| SCHEMBL22941869 | 0.85 | MKNK1 (0.45) | TSHRKMT2AMEN1PRSS1PRSS2 | |
| SCHEMBL13599813 | 0.85 | MKNK1 (0.45) | TSHRKMT2AMEN1PRSS1PRSS2 | |
| SCHEMBL309287 | 0.85 | MKNK1 (0.45) | TSHRKMT2AMEN1PRSS1PRSS2 | |
| SCHEMBL9892953 | 0.84 | LTA4H (0.53) | TSHRALDH1A1CYP3A4TDP1MAPK1 | |
| SCHEMBL260498 | 0.84 | TSHR (0.56) | TSHRALDH1A1CYP3A4TDP1MAPK1 | |
| SCHEMBL11318432 | 0.84 | TSHR (0.56) | TSHRALDH1A1CYP3A4TDP1MAPK1 | |
| SCHEMBL439584 | 0.83 | TSHR (0.59) | TSHRALDH1A1CYP3A4TDP1KMT2A | |
| SCHEMBL279125 | 0.83 | TSHR (0.59) | TSHRALDH1A1CYP3A4TDP1KMT2A | |
| SCHEMBL14488604 | 0.83 | TSHR (0.59) | TSHRALDH1A1CYP3A4TDP1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2616883-B1 | ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR, IMAGE FORMING METHOD, IMAGE FORMING APPARATUS, AND PROCESS CARTRIDGE | RICOH CO LTD (JP) | 2017-09-06 | — | — | EP | disclosed |
| EP-2666059-B1 | ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR, AND IMAGE FORMING METHOD, IMAGE FORMING APPARATUS, AND PROCESS CARTRIDGE USING THE ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR | RICOH CO LTD (JP) | 2016-08-24 | — | — | EP | disclosed |
| US-9201319-B2 | Image bearing member, manufacturing method of the same, image forming method, image forming apparatus, and process cartridge | RICOH COMPANY, LTD. (JP) | 2015-12-01 | — | — | US | disclosed |
| US-9201319-B2 | Image bearing member, manufacturing method of the same, image forming method, image forming apparatus, and process cartridge | RICOH COMPANY, LTD. (JP) | 2015-12-01 | — | — | US | disclosed |
| US-8912348-B2 | Tetrahydropyranyl compound and method for producing the tetrahydropyranyl compound | RICOH COMPANY, LTD. (JP) | 2014-12-16 | — | — | US | disclosed |
| US-8912348-B2 | Tetrahydropyranyl compound and method for producing the tetrahydropyranyl compound | RICOH COMPANY, LTD. (JP) | 2014-12-16 | — | — | US | disclosed |
| US-8771909-B2 | Electrophotographic photoconductor, image forming apparatus, and process cartridge | RICOH COMPANY, LTD. (JP) | 2014-07-08 | — | — | US | disclosed |
| US-20140178810-A1 | IMAGE BEARING MEMBER, MANUFACTURING METHOD OF THE SAME, IMAGE FORMING METHOD, IMAGE FORMING APPARATUS, AND PROCESS CARTRIDGE | RICOH COMPANY, LTD. (JP) | 2014-06-26 | — | — | US | disclosed |
| US-20140178810-A1 | IMAGE BEARING MEMBER, MANUFACTURING METHOD OF THE SAME, IMAGE FORMING METHOD, IMAGE FORMING APPARATUS, AND PROCESS CARTRIDGE | RICOH COMPANY, LTD. (JP) | 2014-06-26 | — | — | US | disclosed |
| US-8679712-B2 | Photoreceptor and image forming method, image forming apparatus, and process cartridge using the photoreceptor | RICOH COMPANY, LTD. (JP) | 2014-03-25 | — | — | US | disclosed |
| US-8679712-B2 | Photoreceptor and image forming method, image forming apparatus, and process cartridge using the photoreceptor | RICOH COMPANY, LTD. (JP) | 2014-03-25 | — | — | US | disclosed |
| US-20130295496-A1 | ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR, AND IMAGE FORMING METHOD, IMAGE FORMING APPARATUS, AND PROCESS CARTRIDGE USING THE ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR | RICOH COMPANY, LTD. (JP) | 2013-11-07 | — | — | US | disclosed |
| US-20130295497-A1 | ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR, IMAGE FORMING METHOD, IMAGE FORMING APPARATUS, AND PROCESS CARTRIDGE | RICOH COMPANY, LTD. (JP) | 2013-11-07 | — | — | US | disclosed |
| US-20130122409-A1 | ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR, IMAGE FORMING APPARATUS, AND PROCESS CARTRIDGE | RICOH COMPANY, LTD. (JP) | 2013-05-16 | — | — | US | disclosed |
| US-20130022903-A1 | PHOTORECEPTOR AND IMAGE FORMING METHOD, IMAGE FORMING APPARATUS, AND PROCESS CARTRIDGE USING THE PHOTORECEPTOR | RICOH COMPANY, LTD. (JP) | 2013-01-24 | — | — | US | disclosed |
| US-20130022903-A1 | PHOTORECEPTOR AND IMAGE FORMING METHOD, IMAGE FORMING APPARATUS, AND PROCESS CARTRIDGE USING THE PHOTORECEPTOR | RICOH COMPANY, LTD. (JP) | 2013-01-24 | — | — | US | disclosed |
| US-20120142948-A1 | TETRAHYDROPYRANYL COMPOUND AND METHOD FOR PRODUCING THE TETRAHYDROPYRANYL COMPOUND | RICOH COMPANY, LTD. (JP) | 2012-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120142948-A1 | TETRAHYDROPYRANYL COMPOUND AND METHOD FOR PRODUCING THE TETRAHYDROPYRANYL COMPOUND | CYP4A11, CYP11B1, CYP11B2 | TSHR 1529/4885ALDH1A1 2275/4885CYP3A4 10/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.