Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | IDO1 | P14902 | 2/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.35 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.35 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.35 |
| ▸ | VHL | P40337 | 1/20 | 0.34 |
| ▸ | ELOC | Q15369 | 1/20 | 0.34 |
| ▸ | ELOB | Q15370 | 1/20 | 0.34 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
| ▸ | CA6 | P23280 | 1/20 | 0.34 |
| ▸ | CA5A | P35218 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL308282 | 0.88 | TSHR (0.48) | TSHRMEN1KMT2ACYP3A4PRSS1 | |
| SCHEMBL14848926 | 0.86 | APP (0.53) | APPIDO1LTA4H | |
| SCHEMBL111405 | 0.85 | — | — | |
| SCHEMBL22941869 | 0.81 | MKNK1 (0.45) | APPTSHRMEN1KMT2APRSS1 | |
| SCHEMBL13599813 | 0.81 | MKNK1 (0.45) | APPTSHRMEN1KMT2APRSS1 | |
| SCHEMBL309287 | 0.81 | MKNK1 (0.45) | APPTSHRMEN1KMT2APRSS1 | |
| SCHEMBL9891695 | 0.81 | TSHR (0.48) | TSHRMEN1KMT2ACYP3A4PRSS1 | |
| SCHEMBL985323 | 0.80 | APP (0.44) | APPTSHRMEN1KMT2ACYP3A4 | |
| SCHEMBL439584 | 0.79 | TSHR (0.59) | TSHRMEN1KMT2ACYP3A4PRSS1 | |
| SCHEMBL15468969 | 0.79 | LPL (0.48) | TSHRMEN1KMT2AIDO1PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9012773-B2 | Thiazole-based compound and uses thereof | NEC CORPORATION (JP) | 2015-04-21 | — | — | US | disclosed |