Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15031999 | 0.80 | ACHE (0.32) | — | |
| SCHEMBL17752372 | 0.78 | S1PR1 (0.33) | — | |
| SCHEMBL21761803 | 0.78 | ACHE (0.33) | — | |
| SCHEMBL10304843 | 0.75 | TTR (0.33) | — | |
| SCHEMBL15028746 | 0.72 | HTR2A (0.40) | — | |
| SCHEMBL10304872 | 0.71 | GABRA1 (0.40) | — | |
| SCHEMBL16527152 | 0.70 | TTR (0.33) | — | |
| SCHEMBL12611014 | 0.70 | KDM1A (0.46) | — | |
| SCHEMBL22597911 | 0.70 | ALDH1A1 (0.39) | — | |
| SCHEMBL32665527 | 0.70 | KDM4E (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9012443-B2 | Bicyclic aryl and heteroaryl sodium channel inhibitors | AMGEN INC. (US) | 2015-04-21 | — | — | US | disclosed |