Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1666014 | 1.00 | ALDH1A1 (0.56) | ALDH1A1TSHRPOLBCYP2C19MEN1 | |
| SCHEMBL3932101 | 0.87 | ALDH1A1 (0.53) | ALDH1A1TSHRPOLBCYP2C19MEN1 | |
| SCHEMBL18400720 | 0.86 | ALDH1A1 (0.55) | ALDH1A1TSHRPOLBCYP2C19MEN1 | |
| SCHEMBL9459074 | 0.83 | ALDH1A1 (0.55) | ALDH1A1TSHRPOLBCYP2C19MEN1 | |
| SCHEMBL9459079 | 0.83 | ALDH1A1 (0.55) | ALDH1A1TSHRPOLBCYP2C19MEN1 | |
| SCHEMBL7478965 | 0.83 | ALDH1A1 (0.59) | ALDH1A1TSHRPOLBCYP2C19MEN1 | |
| SCHEMBL6359410 | 0.83 | ALDH1A1 (0.55) | ALDH1A1TSHRPOLBCYP2C19MEN1 | |
| SCHEMBL4656956 | 0.83 | TSHR (0.52) | ALDH1A1TSHRPOLBCYP2C19MEN1 | |
| SCHEMBL2064880 | 0.82 | ALDH1A1 (0.58) | ALDH1A1TSHRPOLBCYP2C19MEN1 | |
| SCHEMBL26168070 | 0.82 | ALDH1A1 (0.50) | ALDH1A1TSHRPOLBCYP2C19MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2307565-A2 | NUCLEOTIDES AND NUCLEOSIDES AND METHODS FOR THEIR USE IN DNA SEQUENCING | Lasergen, Inc. (US) | 2011-04-13 | — | — | EP | disclosed |
| WO-2009152353-A2 | NUCLEOTIDES AND NUCLEOSIDES AND METHODS FOR THEIR USE IN DNA SEQUENCING | LASERGEN, INC. (US) | 2009-12-17 | — | — | WO | disclosed |