Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1666014 | 0.83 | ALDH1A1 (0.56) | ALDH1A1TSHRHPGDMEN1KMT2A | |
| SCHEMBL1665641 | 0.83 | ALDH1A1 (0.56) | ALDH1A1TSHRHPGDMEN1KMT2A | |
| SCHEMBL7484082 | 0.83 | ALDH1A1 (0.45) | ALDH1A1TSHRHPGDMEN1KMT2A | |
| SCHEMBL3878722 | 0.80 | ALDH1A1 (0.53) | ALDH1A1TSHRHPGDMEN1KMT2A | |
| SCHEMBL68381 | 0.79 | ALDH1A1 (0.70) | ALDH1A1TSHRHPGDMEN1KMT2A | |
| SCHEMBL29699944 | 0.79 | ALDH1A1 (0.70) | ALDH1A1TSHRHPGDMEN1KMT2A | |
| SCHEMBL9459079 | 0.79 | ALDH1A1 (0.55) | ALDH1A1TSHRHPGDMEN1KMT2A | |
| SCHEMBL3096665 | 0.79 | ALDH1A1 (0.55) | ALDH1A1TSHRHPGDMEN1KMT2A | |
| SCHEMBL9459074 | 0.79 | ALDH1A1 (0.55) | ALDH1A1TSHRHPGDMEN1KMT2A | |
| SCHEMBL6359410 | 0.79 | ALDH1A1 (0.55) | ALDH1A1TSHRHPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1227090-A1 | AMINE DERIVATIVES | Tadeka Chemical Industries, Ltd. (JP) | 2002-07-31 | — | — | EP | disclosed |