Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.52 |
| ▸ | MTOR | P42345 | 1/20 | 0.46 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.46 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.42 |
| ▸ | PGR | P06401 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.42 |
| ▸ | MME | P08473 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.41 |
| ▸ | APAF1 | O14727 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27168282 | 0.91 | PGR (0.50) | ALOX5MTORDAGLATRPM8PGR | |
| SCHEMBL7166960 | 0.85 | ALOX5 (0.42) | ALOX5MTORDAGLATRPM8 | |
| SCHEMBL11276344 | 0.84 | POLB (0.48) | ALOX5DAGLAKCNH2MMEPOLB | |
| SCHEMBL13624815 | 0.82 | ALOX5 (0.41) | ALOX5MTORDAGLATRPM8POLB | |
| SCHEMBL12344914 | 0.82 | ALOX5 (0.41) | ALOX5MTORDAGLATRPM8POLB | |
| SCHEMBL28449423 | 0.81 | ALOX5 (0.40) | ALOX5MTORDAGLATRPM8 | |
| SCHEMBL14660341 | 0.81 | ALOX5 (0.49) | ALOX5MTORHTR2AHRH1MTNR1A | |
| SCHEMBL16656812 | 0.80 | ALOX5 (0.51) | ALOX5 | |
| SCHEMBL16656762 | 0.80 | ALOX5 (0.51) | ALOX5 | |
| SCHEMBL16656773 | 0.80 | ALOX5 (0.51) | ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210009508-A1 | Automated Synthesis of Small Molecules Using Chiral, Non-Racemic Boronates | NATIONAL SCIENCE FOUNDATION | 2021-01-14 | — | — | US | disclosed |
| US-10752577-B2 | Automated synthesis of small molecules using chiral, non-racemic boronates | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2020-08-25 | — | — | US | disclosed |
| US-20190315676-A1 | AUTOMATED SYNTHESIS OF SMALL MOLECULES USING CHIRAL, NON-RACEMIC BORONATES | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS | 2019-10-17 | — | — | US | disclosed |
| US-10239824-B2 | Automated synthesis of small molecules using chiral, non-racemic boronates | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2019-03-26 | — | — | US | disclosed |
| US-20170158614-A1 | AUTOMATED SYNTHESIS OF SMALL MOLECULES USING CHIRAL, NON-RACEMIC BORONATES | NATIONAL SCIENCE FOUNDATION | 2017-06-08 | — | — | US | disclosed |
| US-9388131-B2 | Automated synthesis of small molecules using chiral, non-racemic boronates | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2016-07-12 | — | — | US | disclosed |
| US-20150329567-A1 | Automated Synthesis of Small Molecules Using Chiral, Non-Racemic Boronates | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS | 2015-11-19 | — | — | US | disclosed |
| US-9012658-B2 | Automated synthesis of small molecules using chiral, non-racemic boronates | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2015-04-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150329567-A1 | Automated Synthesis of Small Molecules Using Chiral, Non-Racemic Boronates | BTD, POLL, POLR1A | ALOX5 1847/4885MTOR 756/4885DAGLA 2309/4885 |
| US-10752577-B2 | Automated synthesis of small molecules using chiral, non-racemic boronates | BTD, POLL, POLR1A | ALOX5 1847/4885MTOR 756/4885DAGLA 2309/4885 |
| US-20170158614-A1 | AUTOMATED SYNTHESIS OF SMALL MOLECULES USING CHIRAL, NON-RACEMIC BORONATES | BTD, POLL, POLR1A | ALOX5 1847/4885MTOR 756/4885DAGLA 2309/4885 |
| US-20190315676-A1 | AUTOMATED SYNTHESIS OF SMALL MOLECULES USING CHIRAL, NON-RACEMIC BORONATES | BTD, POLL, POLR1A | ALOX5 1847/4885MTOR 756/4885DAGLA 2309/4885 |
| US-10239824-B2 | Automated synthesis of small molecules using chiral, non-racemic boronates | BTD, POLL, POLR1A | ALOX5 1847/4885MTOR 756/4885DAGLA 2309/4885 |
| US-20210009508-A1 | Automated Synthesis of Small Molecules Using Chiral, Non-Racemic Boronates | BTD, POLL, POLR1A | ALOX5 1847/4885MTOR 756/4885DAGLA 2309/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.